1. Epigenetics
  2. MicroRNA
  3. microRNA-21-IN-3

microRNA-21-IN-3 (compound 45) can specifically bind to the precursor of oncogenic and pro-inflammatory microRNA-21 with medium nanomolar affinity, reduce cancer cell proliferation and miR-21 levels, and can be used in antitumor research.

For research use only. We do not sell to patients.

microRNA-21-IN-3 Chemical Structure

microRNA-21-IN-3 Chemical Structure

CAS No. : 2766106-83-4

Size Price Stock Quantity
1 mg USD 125 In-stock
5 mg USD 300 In-stock
10 mg USD 490 In-stock
25 mg USD 1120 In-stock
50 mg USD 1900 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

microRNA-21-IN-3 (compound 45) can specifically bind to the precursor of oncogenic and pro-inflammatory microRNA-21 with medium nanomolar affinity, reduce cancer cell proliferation and miR-21 levels, and can be used in antitumor research[1].

Molecular Weight

323.35

Formula

C16H17N7O

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1N=C(NC2=C1C=CN=C2)NC3=NC=C(N4CCNCC4)C=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (30.93 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0926 mL 15.4631 mL 30.9262 mL
5 mM 0.6185 mL 3.0926 mL 6.1852 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0926 mL 15.4631 mL 30.9262 mL 77.3156 mL
5 mM 0.6185 mL 3.0926 mL 6.1852 mL 15.4631 mL
10 mM 0.3093 mL 1.5463 mL 3.0926 mL 7.7316 mL
15 mM 0.2062 mL 1.0309 mL 2.0617 mL 5.1544 mL
20 mM 0.1546 mL 0.7732 mL 1.5463 mL 3.8658 mL
25 mM 0.1237 mL 0.6185 mL 1.2370 mL 3.0926 mL
30 mM 0.1031 mL 0.5154 mL 1.0309 mL 2.5772 mL
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microRNA-21-IN-3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
microRNA-21-IN-3
Cat. No.:
HY-153534
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