Microtubule inhibitor 11
Microtubule inhibitor 11 (compound 33) is a microtubule inhibitor with a mechanism of action similar to colchicine (HY-N0282). Microtubule inhibitor 11 can be used in cancer-related research.
For research use only. We do not sell to patients.
- Formula: C28H27N3O4
- Molecular Weight:469.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | GI50 |
0.015 μM
Compound: 33
|
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 38865195] |
| PANC-1 | GI50 |
15 nM
Compound: 33
|
Antiproliferative activity against human PANC-1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human PANC-1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 38865195] |
Chemical Information
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Molecular Weight 469.53
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Formula C28H27N3O4
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SMILES
O=C1C2=C(NC(C(C3=CC=C(OCCOCC)C=C3)=O)=C2C4=CC=CC=C4)NC(CCCC#C)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)