2. Cell Cycle/DNA Damage Anti-infection
  3. DNA/RNA Synthesis Bacterial
  4. MRL-436

MRL-436 is a RNA polymerase inhibitor with antibacterial activity. MRL-436 exerts its antibacterial activity dependent on residue 622 of the RNA polymerase β' subunit and the RNAP ω subunit. MRL-436 inhibits Rifampicin (HY-B0272)-resistant RNA polymerase derivatives and exhibits antibacterial activity against Rifampicin-resistant strains.

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MRL-436

MRL-436 화학구조

CAS No. : 2095432-38-3

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MRL-436 Related Antibodies

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제품 설명

MRL-436 is a RNA polymerase inhibitor with antibacterial activity. MRL-436 exerts its antibacterial activity dependent on residue 622 of the RNA polymerase β' subunit and the RNAP ω subunit. MRL-436 inhibits Rifampicin (HY-B0272)-resistant RNA polymerase derivatives and exhibits antibacterial activity against Rifampicin-resistant strains[1].

IC50 & Target

RNA Polymerase

 

분자량

382.46

화학식

C24H22N4O
CAS No.
SMILES

O=C(C1=CC=CN2C1=NN=C2CC(C)C)NC3C4=C(C5=C3C=CC=C5)C=CC=C4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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MRL-436 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MRL-4362095432-38-3MRL436MRL 436DNA/RNA SynthesisBacterialRNA polymeraseantibacterial activity Rifampicin-resistant strainsInhibitorinhibitorinhibit

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상품명:
MRL-436
Cat. No.:
HY-153696
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