Mulberrofuran F
Mulberrofuran F is a Diels-Alder type adduct. Mulberrofuran F exerts antihypertensive effects, exhibits cytotoxicity against human cancer cells, and inhibits the growth of Gram-positive bacteria. Mulberrofuran F can be used in studies related to hypertension and cancer.
For research use only. We do not sell to patients.
- CAS No.: 89200-00-0
- Formula: C39H34O8
- Molecular Weight:630.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
4.9 μg/mL
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Cytotoxicity against human A549 cancer cells, quantified as inhibition of cell growth.
Cytotoxicity against human A549 cancer cells, quantified as inhibition of cell growth.
|
36050566 |
| A2780 | IC50 |
4.6 μg/mL
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Cytotoxicity against human A2780 cancer cells, quantified as inhibition of cell growth.
Cytotoxicity against human A2780 cancer cells, quantified as inhibition of cell growth.
|
36050566 |
| Bel-7402 | IC50 |
4.8 μg/mL
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Cytotoxicity against human Bel-7402 cancer cells, quantified as inhibition of cell growth.
Cytotoxicity against human Bel-7402 cancer cells, quantified as inhibition of cell growth.
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36050566 |
| BGC-823 | IC50 |
5.7 μg/mL
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Cytotoxicity against human BGC-823 cancer cells, quantified as inhibition of cell growth.
Cytotoxicity against human BGC-823 cancer cells, quantified as inhibition of cell growth.
|
36050566 |
| HCT-8 | IC50 |
4.7 μg/mL
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Cytotoxicity against human HCT-8 cancer cells, quantified as inhibition of cell growth.
Cytotoxicity against human HCT-8 cancer cells, quantified as inhibition of cell growth.
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36050566 |
In Vitro
Mulberrofuran F (4.6-5.7 μg/mL) potently inhibits the growth of A549, A2780, Bel-7402, BGC-823, and HCT-8 human cancer cell lines with IC50 values ranging from 4.6 to 5.7 μg/mL[2].
Mulberrofuran F (0.78-6.25 μg/mL) inhibits the growth of multiple Gram-positive bacterial strains, including MRSA and MSSA, with MIC values ranging from 0.78 to 6.25 μg/mL[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 89200-00-0
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Molecular Weight 630.68
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Formula C39H34O8
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SMILES
OC1=CC2=C(C=C(C3=CC(O)=C4C(O[C@]5(C6=CC=C(O)C(C/C=C(C)/C)=C6O)OC7=CC(O)=CC=C7[C@@]8([H])CC(C)=C[C@@]4([H])[C@@]85[H])=C3)O2)C=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. Luo SY, et al. Mulberry Diels-Alder-type adducts: isolation, structure, bioactivity, and synthesis. Natural products and bioprospecting. 2022 Sep 02;12(1):31. [Content Brief]
[3]. Kang J, et al. Five new diels-alder type adducts from the stem and root bark of Morus mongolica. Planta medica. 2006 Jan;72(1):52-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mulberrofuran F Related Classifications
HY-N21970 Related Classifications
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