Myristoyl pentapeptide-4
Based on 1 Customer Validation
Myristoyl pentapeptide-4 is a bioactive peptide with promotion of hair growth effect and has been reported used as a cosmetic ingredient.
For research use only. We do not sell to patients.
- Purity: 98.89%
- CAS No.: 1392416-25-9
- Formula: C37H71N7O10
- Molecular Weight:774.00
-
Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Myristoyl pentapeptide-4 is a synthetic peptide composed of five amino acids with the sequence Lys-Thr-Thr-Lys-Ser (KTTKS)[1].
Myristoyl pentapeptide-4 (10-40 μM, 48 h) specifically targets keratin, activates the transcription and translation of keratin genes, promotes the synthesis of keratin, thereby improving the elasticity and strength of hair[1].
Myristoyl pentapeptide-4 (0-25 μM, 24 h) promotes the proliferation of HaCaT, stimulates the migration of human hair follicle papilla cells (HDPCs)[1].
Myristoyl pentapeptide-4 stimulates skin fibroblasts to produce collagen and fibronectin, thereby reducing wrinkles and improving skin elasticity. Myristoyl pentapeptide-4 also promotes wound healing and skin repair[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:HaCaT
-
Concentration:0-25 μM
-
Incubation Time:24 h
-
Result:Improved the cell viability.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Testosterone induced mouse androgenic alopecia (AGA) model[1]
-
Dosage:500 μL, the concentration remains unknown, but is related to the concentration range in vitro experiments
-
Administration:topical application, once daily for 21 days
-
Result:Increasede the the number of hair follicles, and promoted the hair growth.
Chemical Information
-
CAS No. 1392416-25-9
-
Appearance Solid
-
Molecular Weight 774.00
-
Formula C37H71N7O10
-
Color White to off-white
-
Sequence
{Myr-Lys}-Thr-Thr-Lys-Ser
-
Sequence Shortening
{Myr-Lys}-TTKS
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (161.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2920 mL | 6.4599 mL | 12.9199 mL | 32.2997 mL |
| 5 mM | 0.2584 mL | 1.2920 mL | 2.5840 mL | 6.4599 mL | |
| 10 mM | 0.1292 mL | 0.6460 mL | 1.2920 mL | 3.2300 mL | |
| 15 mM | 0.0861 mL | 0.4307 mL | 0.8613 mL | 2.1533 mL | |
| 20 mM | 0.0646 mL | 0.3230 mL | 0.6460 mL | 1.6150 mL | |
| 25 mM | 0.0517 mL | 0.2584 mL | 0.5168 mL | 1.2920 mL | |
| 30 mM | 0.0431 mL | 0.2153 mL | 0.4307 mL | 1.0767 mL | |
| 40 mM | 0.0323 mL | 0.1615 mL | 0.3230 mL | 0.8075 mL | |
| 50 mM | 0.0258 mL | 0.1292 mL | 0.2584 mL | 0.6460 mL | |
| 60 mM | 0.0215 mL | 0.1077 mL | 0.2153 mL | 0.5383 mL | |
| 80 mM | 0.0161 mL | 0.0807 mL | 0.1615 mL | 0.4037 mL | |
| 100 mM | 0.0129 mL | 0.0646 mL | 0.1292 mL | 0.3230 mL |