1. Anti-infection Metabolic Enzyme/Protease
  2. Influenza Virus Endogenous Metabolite
  3. N-Glycolylneuraminic acid

N-Glycolylneuraminic acid  (Synonyms: NeuGc; GcNeu)

Cat. No.: HY-128965 Purity: 99.90%
COA Handling Instructions

N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs).

For research use only. We do not sell to patients.

N-Glycolylneuraminic acid Chemical Structure

N-Glycolylneuraminic acid Chemical Structure

CAS No. : 1113-83-3

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 132 In-stock
Solution
10 mM * 1 mL in Water USD 132 In-stock
Solid
1 mg USD 57 In-stock
5 mg USD 120 In-stock
10 mg USD 200 In-stock
50 mg USD 520 In-stock
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs)[1].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

325.27

Formula

C11H19NO10

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@]1(O[C@H]([C@@H]([C@H](C1)O)NC(CO)=O)[C@@H]([C@@H](CO)O)O)C(O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 83.33 mg/mL (256.19 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0744 mL 15.3718 mL 30.7437 mL
5 mM 0.6149 mL 3.0744 mL 6.1487 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 10 mg/mL (30.74 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.90%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.0744 mL 15.3718 mL 30.7437 mL 76.8592 mL
5 mM 0.6149 mL 3.0744 mL 6.1487 mL 15.3718 mL
10 mM 0.3074 mL 1.5372 mL 3.0744 mL 7.6859 mL
15 mM 0.2050 mL 1.0248 mL 2.0496 mL 5.1239 mL
20 mM 0.1537 mL 0.7686 mL 1.5372 mL 3.8430 mL
25 mM 0.1230 mL 0.6149 mL 1.2297 mL 3.0744 mL
30 mM 0.1025 mL 0.5124 mL 1.0248 mL 2.5620 mL
40 mM 0.0769 mL 0.3843 mL 0.7686 mL 1.9215 mL
50 mM 0.0615 mL 0.3074 mL 0.6149 mL 1.5372 mL
60 mM 0.0512 mL 0.2562 mL 0.5124 mL 1.2810 mL
80 mM 0.0384 mL 0.1921 mL 0.3843 mL 0.9607 mL
100 mM 0.0307 mL 0.1537 mL 0.3074 mL 0.7686 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N-Glycolylneuraminic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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N-Glycolylneuraminic acid
Cat. No.:
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