2. Anti-infection Metabolic Enzyme/Protease
  3. Influenza Virus Endogenous Metabolite
  4. N-Glycolylneuraminic acid

N-グリコリルノイラミン酸  (Synonyms: N-Glycolylneuraminic acid)

製品番号: HY-128965 純度: 99.76%
COA 取扱説明書 Technical Support

N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs).

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N-Glycolylneuraminic acid

N-グリコリルノイラミン酸 構造式

CAS 番号 : 1113-83-3

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 104 在庫あり
Solution
10 mM * 1 mL in Water USD 104 在庫あり
Solid
5 mg $95 在庫あり
10 mg $160 在庫あり
25 mg $295 在庫あり
50 mg $480 在庫あり
100 mg $695 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

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Other Forms of N-Glycolylneuraminic acid:

N-グリコリルノイラミン酸 関連抗体

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製品説明

N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs)[1].

IC50 & Target

Human Endogenous Metabolite

 

体外実験

N-Glycolylneuraminic acid (0.5-2 mM, 3 days) binds to the influenza virus HA protein, preventing the virus from entering A549 cell[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

N-グリコリルノイラミン酸 関連抗体
体内実験

N-Glycolylneuraminic acid (sc, single dose) promotes the formation of experimental lung tumor nodules, especially macronodules in mouse 3LL Lewis lung carcinoma models[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mouse 3LL Lewis lung carcinoma models[2]
Dosage:
Administration: sc, single dose
Result: Increased the number of total lung tumor nodules and macronodules.
分子量

325.27

分子式

C11H19NO10
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O[C@@]1(O[C@H]([C@@H]([C@H](C1)O)NC(CO)=O)[C@@H]([C@@H](CO)O)O)C(O)=O
Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

H2O : 83.33 mg/mL (256.19 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0744 mL 15.3718 mL 30.7437 mL
5 mM 0.6149 mL 3.0744 mL 6.1487 mL
10 mM 0.3074 mL 1.5372 mL 3.0744 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 10 mg/mL (30.74 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.76%

COA (251 KB) HNMR (253 KB) RP-HPLC (206 KB) MS (71 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.0744 mL 15.3718 mL 30.7437 mL 76.8592 mL
5 mM 0.6149 mL 3.0744 mL 6.1487 mL 15.3718 mL
10 mM 0.3074 mL 1.5372 mL 3.0744 mL 7.6859 mL
15 mM 0.2050 mL 1.0248 mL 2.0496 mL 5.1239 mL
20 mM 0.1537 mL 0.7686 mL 1.5372 mL 3.8430 mL
25 mM 0.1230 mL 0.6149 mL 1.2297 mL 3.0744 mL
30 mM 0.1025 mL 0.5124 mL 1.0248 mL 2.5620 mL
40 mM 0.0769 mL 0.3843 mL 0.7686 mL 1.9215 mL
50 mM 0.0615 mL 0.3074 mL 0.6149 mL 1.5372 mL
60 mM 0.0512 mL 0.2562 mL 0.5124 mL 1.2810 mL
80 mM 0.0384 mL 0.1921 mL 0.3843 mL 0.9607 mL
100 mM 0.0307 mL 0.1537 mL 0.3074 mL 0.7686 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N-Glycolylneuraminic acid Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Glycolylneuraminic acid1113-83-3NeuGc GcNeuInfluenza VirusEndogenous MetaboliteInhibitorinhibitorinhibit

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