N-Myristoyl-D-asparagine
Based on 1 Customer Validation
N-Myristoyl-D-asparagine is a key metabolic marker in the biosynthesis and maturation of colibactin. N-Myristoyl-D-asparagine acts as a biomarker for detecting colibactin. N-Myristoyl-D-asparagine exhibits mild growth inhibitory activity against Bacillus subtilis NCIB 3610.
For research use only. We do not sell to patients.
- Purity : 96.57%
- CAS No.: 1439789-50-0
- Formula: C18H34N2O4
- Molecular Weight:342.47
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
N-Myristoyl-D-asparagine is released during colibactin maturation and serves as a biomarker for colibactin production by Escherichia coli Nissle and related strains[1].
N-Myristoyl-D-asparagine is a prodrug precursor fragment cleaved from the putative colibactin precursor by the peptidase ClbP[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1439789-50-0
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Appearance Solid
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Molecular Weight 342.47
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Formula C18H34N2O4
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Color White to off-white
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SMILES
CCCCCCCCCCCCCC(N[C@@H](C(O)=O)CC(N)=O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (263 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Kalantari A, et al. Robust performance of a live bacterial therapeutic chassis lacking the colibactin gene cluster. PLoS One. 2023;18(2):e0280499. Published 2023 Feb 2. [Content Brief]
[2].
Bian X, et al. Two more pieces of the colibactin genotoxin puzzle from Escherichia coli show incorporation of an unusual 1-aminocyclopropanecarboxylic acid moiety. Chem Sci. 2015 May 1;6(5):3154-3160.
[Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)