N,N-Bis(3-aminopropyl)dodecylamine
Based on 1 Customer Validation
N,N-Bis(3-aminopropyl)dodecylamine is a potent fungicidal agent with remarkable activity against Aspergillus niger. N,N-Bis(3-aminopropyl)dodecylamine induces oxidative stress and regulates the activities of multiple antioxidant and mitochondrial enzymes in a concentration‑ and duration‑dependent manner. N,N-Bis(3-aminopropyl)dodecylamine disrupts fungal organelles, remodels mitochondrial morphology and impairs mitochondria‑related cellular functions. N,N-Bis(3-aminopropyl)dodecylamine can be used for the research of fungicidal mechanisms and oxidative stress in Aspergillus niger.
For research use only. We do not sell to patients.
- Purity : 98.80%
- CAS No.: 2372-82-9
- Formula: C18H41N3
- Molecular Weight:299.55
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
N,N-Bis(3-aminopropyl)dodecylamine (apd) (0.05-0.1%, v/v; 1-24 h) modulates antioxidant and mitochondrial enzyme activities in Aspergillus niger mycelium in a concentration‑ and time‑dependent manner. It markedly increases total SOD, CAT, GSP, SDG and NDG activities at 4 h, and restores FHT activity after an initial reduction, with CAT activity peaking at 344% of the control[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2372-82-9
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Appearance Liquid (Density: 0.9±0.1 g/cm3)
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Molecular Weight 299.55
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Formula C18H41N3
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Color Colorless to light yellow
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SMILES
NCCCN(CCCN)CCCCCCCCCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
H2O : 40 mg/mL (133.53 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (950 KB)
- English - EN (950 KB)
- Français - FR (950 KB)
- Deutsch - DE (950 KB)
- Norwegian - NO (950 KB)
- Español - ES (950 KB)
- Swedish - SV (950 KB)
- Italian - IT (950 KB)
- Korean - KR (950 KB)
- Portuguese - PT (950 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.3383 mL | 16.6917 mL | 33.3834 mL | 83.4585 mL |
| 5 mM | 0.6677 mL | 3.3383 mL | 6.6767 mL | 16.6917 mL | |
| 10 mM | 0.3338 mL | 1.6692 mL | 3.3383 mL | 8.3459 mL | |
| 15 mM | 0.2226 mL | 1.1128 mL | 2.2256 mL | 5.5639 mL | |
| 20 mM | 0.1669 mL | 0.8346 mL | 1.6692 mL | 4.1729 mL | |
| 25 mM | 0.1335 mL | 0.6677 mL | 1.3353 mL | 3.3383 mL | |
| 30 mM | 0.1113 mL | 0.5564 mL | 1.1128 mL | 2.7820 mL | |
| 40 mM | 0.0835 mL | 0.4173 mL | 0.8346 mL | 2.0865 mL | |
| 50 mM | 0.0668 mL | 0.3338 mL | 0.6677 mL | 1.6692 mL | |
| 60 mM | 0.0556 mL | 0.2782 mL | 0.5564 mL | 1.3910 mL | |
| 80 mM | 0.0417 mL | 0.2086 mL | 0.4173 mL | 1.0432 mL | |
| 100 mM | 0.0334 mL | 0.1669 mL | 0.3338 mL | 0.8346 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.