N,N-Bis(3-aminopropyl)dodecylamine

Cat. No.: HY-W032878 Purity: 98.80%: Data Sheet
COA

SDS
Handling Instructions
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N,N-Bis(3-aminopropyl)dodecylamine is a potent fungicidal agent with remarkable activity against Aspergillus niger. N,N-Bis(3-aminopropyl)dodecylamine induces oxidative stress and regulates the activities of multiple antioxidant and mitochondrial enzymes in a concentration‑ and duration‑dependent manner. N,N-Bis(3-aminopropyl)dodecylamine disrupts fungal organelles, remodels mitochondrial morphology and impairs mitochondria‑related cellular functions. N,N-Bis(3-aminopropyl)dodecylamine can be used for the research of fungicidal mechanisms and oxidative stress in Aspergillus niger.

For research use only. We do not sell to patients.

N,N-Bis(3-aminopropyl)dodecylamine Chemical Structure

CAS No. : 2372-82-9

Size	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	In-stock	Estimated Time of Arrival: December 31
Liquid
100 mg	In-stock	Estimated Time of Arrival: December 31
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	Get quote	Estimated Time of Arrival: December 31
10 g	Get quote
50 g	Get quote

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Description

In Vitro

N,N-Bis(3-aminopropyl)dodecylamine (apd) (0.05-0.1%, v/v; 1-24 h) modulates antioxidant and mitochondrial enzyme activities in Aspergillus niger mycelium in a concentration‑ and time‑dependent manner. It markedly increases total SOD, CAT, GSP, SDG and NDG activities at 4 h, and restores FHT activity after an initial reduction, with CAT activity peaking at 344% of the control^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

299.55

Formula

C₁₈H₄₁N₃

CAS No.

2372-82-9

Appearance

Liquid

Color

Colorless to light yellow

SMILES

NCCCN(CCCN)CCCCCCCCCCCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 40 mg/mL (133.53 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3383 mL	16.6917 mL	33.3834 mL
5 mM	0.6677 mL	3.3383 mL	6.6767 mL
10 mM	0.3338 mL	1.6692 mL	3.3383 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.80%

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Data Sheet (266 KB) SDS (950 KB)

COA (240 KB) HNMR (252 KB) LCMS (318 KB)

Handling Instructions (2659 KB)

References

[1]. Kuźniak E, et al. Effects of N,N-bis(3-aminopropyl)dodecylamine on antioxidant enzyme activities, mitochondrial morphology and metabolism in Aspergillus niger. Folia Microbiol (Praha). 2006;51(1):38-44. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.3383 mL	16.6917 mL	33.3834 mL	83.4585 mL
	5 mM	0.6677 mL	3.3383 mL	6.6767 mL	16.6917 mL
	10 mM	0.3338 mL	1.6692 mL	3.3383 mL	8.3459 mL
	15 mM	0.2226 mL	1.1128 mL	2.2256 mL	5.5639 mL
	20 mM	0.1669 mL	0.8346 mL	1.6692 mL	4.1729 mL
	25 mM	0.1335 mL	0.6677 mL	1.3353 mL	3.3383 mL
	30 mM	0.1113 mL	0.5564 mL	1.1128 mL	2.7820 mL
	40 mM	0.0835 mL	0.4173 mL	0.8346 mL	2.0865 mL
	50 mM	0.0668 mL	0.3338 mL	0.6677 mL	1.6692 mL
	60 mM	0.0556 mL	0.2782 mL	0.5564 mL	1.3910 mL
	80 mM	0.0417 mL	0.2086 mL	0.4173 mL	1.0432 mL
	100 mM	0.0334 mL	0.1669 mL	0.3338 mL	0.8346 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.