Neuropeptide Y (1-24) (human)
Neuropeptide Y (1-24) (human) is a neuropeptide with potencies in inhibiting the electricity stimulated twitch response of rat vas deferens. Neuropeptide Y (1-24) (human) stimulates N-methyl-D-aspartate (NMDA)-induced neuronal activation in the rat CA3 region of the dorsal hippocampus in vivo.
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- CAS No.: 131448-51-6
- Formula: C116H170N30O40S
- Molecular Weight:2656.83
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Storage:
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Neuropeptide Y Receptor Isoforms
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Biological Activity
Neuropeptide Y (1-24) (human) dose-dependently enhances N-methyl-D-aspartate (NMDA)-induced activation of CA3 dorsal hippocampus pyramidal neurons[1].
Neuropeptide Y (1-24) (human) selectively increases the amplitude of the twitch response to electrical stimulation at low micromolar concentrations but shows no affinity toward [3H]NPY brain receptor sites and no inhibition of the twitch response in the rat vas deferens preparation at concentrations up to 1.0 mM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 131448-51-6
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Molecular Weight 2656.83
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Formula C116H170N30O40S
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Sequence Shortening
YPSKPDNPGEDAPAEDMARYYSAL-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Monnet FP, et al. Neuropeptide Y potentiates selectively the N-methyl-D-aspartate response in the rat CA3 dorsal hippocampus. I. Involvement of an atypical neuropeptide Y receptor. J Pharmacol Exp Ther. 1992 Dec;263(3):1212-8. [Content Brief]
[2]. Martel JC, et al Comparative structural requirements of brain neuropeptide Y binding sites and vas deferens neuropeptide Y receptors. Mol Pharmacol. 1990 Oct;38(4):494-502. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Neuropeptide Y (1-24) (human) Related Classifications
HY-P3679 Related Classifications
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