2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. O-Demethyl Lenvatinib

O-Demethyl Lenvatinib is a metabolite of Lenvatinib (HY-10981). Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (O-Demethyl Lenvatinib hydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

O-Demethyl Lenvatinib Chemical Structure

O-Demethyl Lenvatinib Chemical Structure

CAS No. : 417717-04-5

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O-Demethyl Lenvatinib Related Antibodies

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Description

O-Demethyl Lenvatinib is a metabolite of Lenvatinib (HY-10981). Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2].

Molecular Weight

412.83

Formula

C20H17ClN4O4
CAS No.
SMILES

O=C(C1=C(O)C=C2N=CC=C(OC3=CC=C(NC(NC4CC4)=O)C(Cl)=C3)C2=C1)N
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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O-Demethyl Lenvatinib Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

O-Demethyl Lenvatinib417717-04-5Drug MetaboliteInhibitorinhibitorinhibit

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