1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. Oxybuprocaine hydrochloride

Oxybuprocaine hydrochloride (Synonyms: Benoxinate hydrochloride)

Cat. No.: HY-B1288 Purity: >98.0%
Handling Instructions

Oxybuprocaine hydrochloride (Benoxinate hydrochloride) reversibly blocks sodium channels and prevents propagation of painful nerve impulses in the cornea, conjunctiva, and sclera. Oxybuprocaine hydrochloride is used especially in ophthalmology and otolaryngology.

For research use only. We do not sell to patients.

Oxybuprocaine hydrochloride Chemical Structure

Oxybuprocaine hydrochloride Chemical Structure

CAS No. : 5987-82-6

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 99 In-stock
Estimated Time of Arrival: December 31
50 mg USD 90 In-stock
Estimated Time of Arrival: December 31
100 mg USD 150 In-stock
Estimated Time of Arrival: December 31
250 mg USD 290 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
1 g   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Oxybuprocaine hydrochloride (Benoxinate hydrochloride) reversibly blocks sodium channels and prevents propagation of painful nerve impulses in the cornea, conjunctiva, and sclera. Oxybuprocaine hydrochloride is used especially in ophthalmology and otolaryngology[1][2][3].

In Vivo

Oxybuprocaine hydrochloride (Benoxinate hydrochloride; 27.6, 51.7, 103.5, 413.9 μg; s.c.) provides a dose-dependent block to pinpricks in rats[1].
Oxybuprocaine hydrochloride (27.6 μg) produces 100% of sensory/nociceptive block[1].

Animal Model: Male Sprague-Dawley rats (203-253 g)[1]
Dosage: 27.6, 51.7, 103.5, 413.9 μg
Administration: SC
Result: Provided a dose-dependent block to pinpricks.
Molecular Weight

344.88

Formula

C₁₇H₂₉ClN₂O₃

CAS No.

5987-82-6

SMILES

O=C(OCCN(CC)CC)C1=CC=C(N)C(OCCCC)=C1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

OxybuprocaineBenoxinateSodium ChannelNa channelsNa+ channelspropagationpainfulnerveimpulsescorneaconjunctivascleraophthalmologyotolaryngologyALOParkinson’sdiseaseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Oxybuprocaine hydrochloride
Cat. No.:
HY-B1288
Quantity:
MCE Japan Authorized Agent: