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Cat. No.: HY-174977

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P2Y12R ligand-1

P2Y12R ligand-1 (Compound 41) is a high-affinity P2Y₁₂R ligand with a K_i value of 17.1 nM. P2Y12R ligand-1 labeled with [¹⁸F] can be used in studies of brain PET imaging.

For research use only. We do not sell to patients.

Formula: C₃₂H₃₅ClFN₅O₃
Molecular Weight:592.10

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

P2Y12R ligand-1 Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

P2Y12R ligand-1 (Compound 41) is a high-affinity P2Y₁₂R ligand with a K_i value of 17.1 nM. P2Y12R ligand-1 labeled with [¹⁸F] can be used in studies of brain PET imaging^[1].

All P2Y Receptor Isoforms :

Chemical Information

Molecular Weight 592.10
Formula C₃₂H₃₅ClFN₅O₃
SMILES

CCCC(C1=C(N(N=C1)C2=CC=C(C=C2)NC(C3=CN(C4=CC=C(C=C34)Cl)CC(N5CCC(CC5)CCF)=O)=O)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pincemail E, et al. Synthesis, Labeling, and Biological Evaluation of P2Y12 Receptor Radioligands for Positron Emission Tomography Imaging of Neuroinflammation. ACS Chem Neurosci. 2025 Jul 16;16(14):2639-2656. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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P2Y12R ligand-1

All P2Y Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

P2Y12R ligand-1 Related Classifications

HY-174977 Related Classifications