Palonosetron hydrochloride (Standard)
Palonosetron hydrochloride (Standard) is the analytical standard of Palonosetron hydrochloride (HY-A0021). This product is intended for research and analytical applications. Palonosetron hydrochloride is a 5-HT3 antagonist primarily used to prevent acute, delayed, and overall chemotherapy-induced nausea and vomiting. In addition, Palonosetron hydrochloride exhibits moderate anti-flavivirus activity and potent anti-Zika virus activity in mammalian cells. Palonosetron hydrochloride also possesses antidepressant activity.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 135729-62-3
- Formula: C19H25ClN2O
- Molecular Weight:332.87
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
-
HY-A0021
Palonosetron hydrochloride -
HY-15066
CNQX -
HY-70050C
Alosetron Hydrochloride -
HY-B0404A
Benserazide hydrochloride -
HY-B0750
Dolasetron -
HY-B0071A
Granisetron Hydrochloride -
HY-11100
Asenapine maleate -
HY-B0595R
Ramosetron Hydrochloride (Standard) -
HY-14336A
SB 271046 Hydrochloride -
HY-B0731
Perospirone hydrochloride -
HY-B0595
Ramosetron Hydrochloride -
HY-B0404AR
Benserazide hydrochloride (Standard)
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 135729-62-3
-
Molecular Weight 332.87
-
Formula C19H25ClN2O
-
SMILES
O=C1N(C[C@@]([H])(CCC2)C3=C2C=CC=C13)[C@@H]4CN5CCC4CC5.[H]Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Vishnu Murthy M, Srinivas K, Kumar R, Mukkanti K. Development and validation of a stability-indicating LC method for determining palonosetron hydrochloride, its related compounds and degradation products using naphthalethyl stationary phase. J Pharm Biomed Anal. 2011 Sep 10;56(2):429-35. [Content Brief]
[2]. Ajioka H, Morita F, Akizawa Y, Yoshida K, Kitamura R, Takimoto H. Pharmacological, pharmacokinetic, and clinical profile of palonosetron hydrochloride (ALOXI I.V. Injection 0.75 mg), a novel antiemetic 5-HT3-receptor antagonist.Nihon Yakurigaku Zasshi. 2010 Aug;136(2):113-20. [Content Brief]
[3]. Ruhlmann C, Herrstedt J. Palonosetron hydrochloride for the prevention of chemotherapy-induced nausea and vomiting. Expert Rev Anticancer Ther. 2010 Feb;10(2):137-48. [Content Brief]
[4]. Trissel LA, Trusley C, Ben M, Kupiec TC. Physical and chemical stability of palonosetron hydrochloride with five opiate agonists during simulated Y-site administration. Am J Health Syst Pharm. 2007 Jun 1;64(11):1209-13. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Palonosetron hydrochloride (Standard) Related Classifications
HY-A0021R Related Classifications
Powered by Bioz