2. Immunology/Inflammation
  3. PD-1/PD-L1 VISTA
  4. PD-L1/VISTA-IN-1

PD-L1/VISTA-IN-1 (Compound P17) is an orally active dual-target inhibitor of PD-L1 and VISTA. PD-L1/VISTA-IN-1 can block the PD-1/PD-L1 interaction (IC50: 0.1492 μM) and the VISTA pathway (KD: 0.2723 μM), thereby reactivating T cells. PD-L1/VISTA-IN-1 has anti-tumor activity.

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PD-L1/VISTA-IN-1

PD-L1/VISTA-IN-1 화학구조

CAS No. : 2978623-09-3

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PD-L1/VISTA-IN-1 Related Antibodies

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제품 설명

PD-L1/VISTA-IN-1 (Compound P17) is an orally active dual-target inhibitor of PD-L1 and VISTA. PD-L1/VISTA-IN-1 can block the PD-1/PD-L1 interaction (IC50: 0.1492 μM) and the VISTA pathway (KD: 0.2723 μM), thereby reactivating T cells. PD-L1/VISTA-IN-1 has anti-tumor activity[1].

분자량

408.45

화학식

C22H24N4O4
CAS No.
SMILES

CC1=C(C=CC=C1C2=CC=CC=C2)NC3=NC(OC)=CC(CN[C@H](C(O)=O)CO)=N3
선적

Room temperature in continental US; may vary elsewhere.
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순도&문서
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PD-L1/VISTA-IN-1 Related Classifications

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Keywords:

PD-L1/VISTA-IN-12978623-09-3PD-1/PD-L1VISTAPD-1/Programmed death-ligand 1V-domain Ig suppressor of T cell activation (VISTA)A549H1975PBMC293TLung cancer modelInhibitorinhibitorinhibit

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상품명:
PD-L1/VISTA-IN-1
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HY-170793
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