PD-L1/VISTA-IN-1
PD-L1/VISTA-IN-1 (Compound P17) is an orally active dual-target inhibitor of PD-L1 and VISTA. PD-L1/VISTA-IN-1 can block the PD-1/PD-L1 interaction (IC50: 0.1492 μM) and the VISTA pathway (KD: 0.2723 μM), thereby reactivating T cells. PD-L1/VISTA-IN-1 has anti-tumor activity.
For research use only. We do not sell to patients.
- CAS No.: 2978623-09-3
- Formula: C22H24N4O4
- Molecular Weight:408.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2978623-09-3
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Molecular Weight 408.45
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Formula C22H24N4O4
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SMILES
CC1=C(C=CC=C1C2=CC=CC=C2)NC3=NC(OC)=CC(CN[C@H](C(O)=O)CO)=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)