pEBOV-IN-1
Based on 1 Customer Validation
pEBOV-IN-1 (Comp 2) is a pEBOV inhibitor, with an EC50 value of 0.38 μM. pEBOV: pseudotyped Ebola virus.
For research use only. We do not sell to patients.
- Purity : 98.29%
- CAS No.: 1252187-41-9
- Formula: C29H36N2O
- Molecular Weight:428.61
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
IC50 & Target
|
EBOV |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero | EC50 |
0.38 μM
Compound: 2
|
Inhibition of glycoprotein in VSV pseudotyped Ebolavirus infected in African green monkey Vero cells assessed as reduction in virus entry incubated for 24 hrs by luciferase reporter gene assay
Inhibition of glycoprotein in VSV pseudotyped Ebolavirus infected in African green monkey Vero cells assessed as reduction in virus entry incubated for 24 hrs by luciferase reporter gene assay
|
[PMID: 32550996] |
Chemical Information
-
CAS No. 1252187-41-9
-
Appearance Solid
-
Molecular Weight 428.61
-
Formula C29H36N2O
-
Color White to off-white
-
SMILES
O=C([C@@]12C[C@@](C[C@@H]3C2)(C4=CC=CC=C4)C[C@H](C3)C1)NC(CC5)CCN5CC6=CC=CC=C6
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 16.67 mg/mL (38.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (269 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3331 mL | 11.6656 mL | 23.3312 mL | 58.3281 mL |
| 5 mM | 0.4666 mL | 2.3331 mL | 4.6662 mL | 11.6656 mL | |
| 10 mM | 0.2333 mL | 1.1666 mL | 2.3331 mL | 5.8328 mL | |
| 15 mM | 0.1555 mL | 0.7777 mL | 1.5554 mL | 3.8885 mL | |
| 20 mM | 0.1167 mL | 0.5833 mL | 1.1666 mL | 2.9164 mL | |
| 25 mM | 0.0933 mL | 0.4666 mL | 0.9332 mL | 2.3331 mL | |
| 30 mM | 0.0778 mL | 0.3889 mL | 0.7777 mL | 1.9443 mL |