Perfluorohexylsulfonyl fluoride
Based on 1 Customer Validation
Perfluorohexylsulfonyl fluoride (Perfluorohexanesulphonyl fluoride) is a perfluoroalkyl and polyfluoroalkyl substances, that is defined as persistant organic pollutant by 2022 Stockholm Convention. Perfluorohexylsulfonyl fluoride can be used for drug modification.
For research use only. We do not sell to patients.
- Purity: 97.10%
- CAS No.: 423-50-7
- Formula: C6F14O2S
- Molecular Weight:402.11
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 423-50-7
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Appearance Liquid (Density: 1.786±0.06 g/cm3)
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Molecular Weight 402.11
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Formula C6F14O2S
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Color Colorless to light yellow
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SMILES
O=S(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(F)=O
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Synonyms
Perfluorohexanesulphonyl fluoride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (124.34 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (12.43 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (12.43 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (627 KB)
- English - EN (627 KB)
- Français - FR (627 KB)
- Deutsch - DE (627 KB)
- Norwegian - NO (627 KB)
- Español - ES (627 KB)
- Swedish - SV (627 KB)
- Italian - IT (627 KB)
- Korean - KR (627 KB)
- Portuguese - PT (627 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4869 mL | 12.4344 mL | 24.8688 mL | 62.1720 mL |
| 5 mM | 0.4974 mL | 2.4869 mL | 4.9738 mL | 12.4344 mL | |
| 10 mM | 0.2487 mL | 1.2434 mL | 2.4869 mL | 6.2172 mL | |
| 15 mM | 0.1658 mL | 0.8290 mL | 1.6579 mL | 4.1448 mL | |
| 20 mM | 0.1243 mL | 0.6217 mL | 1.2434 mL | 3.1086 mL | |
| 25 mM | 0.0995 mL | 0.4974 mL | 0.9948 mL | 2.4869 mL | |
| 30 mM | 0.0829 mL | 0.4145 mL | 0.8290 mL | 2.0724 mL | |
| 40 mM | 0.0622 mL | 0.3109 mL | 0.6217 mL | 1.5543 mL | |
| 50 mM | 0.0497 mL | 0.2487 mL | 0.4974 mL | 1.2434 mL | |
| 60 mM | 0.0414 mL | 0.2072 mL | 0.4145 mL | 1.0362 mL | |
| 80 mM | 0.0311 mL | 0.1554 mL | 0.3109 mL | 0.7772 mL | |
| 100 mM | 0.0249 mL | 0.1243 mL | 0.2487 mL | 0.6217 mL |
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