Polyvinylpyrrolidone, average Mw~360000
Based on 1 Customer Validation
Polyvinylpyrrolidone, average Mw~360000 is a multifunctional synthetic polymer with an average molecular weight of 360000 Da. Polyvinylpyrrolidone, average Mw~360000 is widely used to synthesize nanoparticlesPolyvinylpyrrolidone, average Mw~360000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc.
For research use only. We do not sell to patients.
- CAS No.: 9003-39-8
- Formula: (C6H9NO)n
- Molecular Weight:360000 (Average)
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Storage:Powder -20°C, 3 years
Biological Activity
Polyvinylpyrrolidone (PVP), a non-ionic polymer, has been employed in multifarious fields such as paper, fibers and textiles, ceramics, and pharmaceutics due to its superior properties. Especially in pharmacy, the properties of inertness, non-toxicity, and biocompatibility make it a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc. Polyvinylpyrrolidone with different molecular weights (MWs) and concentrations is used in a variety of formulations for different purposes. The main pharmaceutical applications of Polyvinylpyrrolidone as follows: (i) improving the bioavailability and stability of drugs, (ii) improving the physicomechanical properties of preparations, (iii) adjusting the release rate of drugs, and (iv) prolonging the in vivo circulation time of liposomes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9003-39-8
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Appearance Solid
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Molecular Weight 360000 (Average)
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Formula (C6H9NO)n
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Color White to off-white
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SMILES
O=C1CCCN1C(C[H])[H].[n]
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Synonyms
PVP, average Mw~360000; Polyvidone, average Mw~360000; Povidone, average Mw~360000
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years
Solvent & Solubility
DMSO : 20 mg/mL (ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (455 KB)
- English - EN (455 KB)
- Français - FR (455 KB)
- Deutsch - DE (455 KB)
- Norwegian - NO (455 KB)
- Español - ES (455 KB)
- Swedish - SV (455 KB)
- Italian - IT (455 KB)
- Korean - KR (455 KB)
- Portuguese - PT (455 KB)
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Handling Instructions (2659 KB)
References
[1]. Konietzka J, et al. Epidermal Growth Factor Signaling Promotes Sleep through a Combined Series and Parallel Neural Circuit. Curr Biol. 2020 Jan 6;30(1):1-16.e13. [Content Brief]
[2]. Luo Y, et al. Multifunctional Role of Polyvinylpyrrolidone in Pharmaceutical Formulations. AAPS PharmSciTech. 2021 Jan 6;22(1):34. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)