Polyvinylpyrrolidone K25
Based on 1 Customer Validation
Polyvinylpyrrolidone K25 is a multifunctional synthetic polymer. Polyvinylpyrrolidone K25 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems. Polyvinylpyrrolidone K25 is a preferable binder for granules and tablets.
For research use only. We do not sell to patients.
- CAS No.: 9003-39-8
- Formula: (C6H9NO)n
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Storage:
4°C, protect from light, stored under nitrogen
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Polyvinylpyrrolidone K25 prevents or retard drug crystallization from the supersaturated system by inhibiting nucleation and/or crystal growth and allows for complete drug release[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 9003-39-8
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Appearance Solid
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Formula (C6H9NO)n
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Color White to off-white
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SMILES
O=C1CCCN1C(C[H])[H].[n]
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Synonyms
PVP K25; Polyvidone K25; Povidone K25
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
Solvent & Solubility
DMSO : 200 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 100 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Luo Y, et al. Multifunctional Role of Polyvinylpyrrolidone in Pharmaceutical Formulations. AAPS PharmSciTech. 2021 Jan 6;22(1):34. [Content Brief]
[2]. Van den Mooter G, et al. Physical stabilisation of amorphous ketoconazole in solid dispersions with polyvinylpyrrolidone K25. Eur J Pharm Sci. 2001 Jan;12(3):261-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Polyvinylpyrrolidone K25 Related Classifications
HY-B1620D Related Classifications
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- Polyvinylpyrrolidone K25
- 9003-39-8
- PVP K25
- Polyvidone K25
- Povidone K25
- Polyvinylpyrrolidone K 25
- Polyvinylpyrrolidone K-25
- PVP K 25
- PVP K-25
- Polyvidone K25
- Polyvidone K 25
- Polyvidone K-25
- Povidone K25
- Povidone K 25
- Povidone K-25
- Biochemical Assay Reagents
- pharmaceutical preparations
- binder
- coating agent
- suspending agent
- pore-former
- solubilizer
- stabilizer
- Inhibitor
- inhibitor
- inhibit