Polyvinylpyrrolidone, average Mw~1300000
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Polyvinylpyrrolidone, average Mw~1300000 is a multifunctional synthetic polymer with an average molecular weight of 1300000 Da. Polyvinylpyrrolidone, average Mw~1300000 shows the higher viscosity to form the fine polymer network as the molecular sieve.
For research use only. We do not sell to patients.
- CAS No.: 9003-39-8
- Formula: (C6H9NO)n
- Molecular Weight:1300000 (Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Polyvinylpyrrolidone (PVP), a non-ionic polymer, has been employed in multifarious fields such as paper, fibers and textiles, ceramics, and pharmaceutics due to its superior properties. Especially in pharmacy, the properties of inertness, non-toxicity, and biocompatibility make it a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc. Polyvinylpyrrolidone with different molecular weights (MWs) and concentrations is used in a variety of formulations for different purposes. The main pharmaceutical applications of Polyvinylpyrrolidone as follows: (i) improving the bioavailability and stability of drugs, (ii) improving the physicomechanical properties of preparations, (iii) adjusting the release rate of drugs, and (iv) prolonging the in vivo circulation time of liposomes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9003-39-8
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Appearance Solid
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Molecular Weight 1300000 (Average)
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Formula (C6H9NO)n
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Color White to off-white
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SMILES
O=C1CCCN1C(C[H])[H].[n]
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Synonyms
PVP, average Mw~1300000; Polyvidone, average Mw~1300000; Povidone, average Mw~1300000
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
H2O : 14.29 mg/mL (ultrasonic and warming and heat to 60°C)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Yamashita T, et al. Influence of oligonucleotides structures for separation of diastereomers by capillary electrophoresis method using polyvinylpyrrolidone 1,300,000. J Chromatogr A. 2024 Jun 21;1725:464945. [Content Brief]
[2]. Luo Y, et al. Multifunctional Role of Polyvinylpyrrolidone in Pharmaceutical Formulations. AAPS PharmSciTech. 2021 Jan 6;22(1):34. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)