Pomalidomide-5-C4-NH2 hydrochloride
Based on 1 Customer Validation
Pomalidomide-5-C4-NH2 hydrochloride is the Pomalidomide (HY-10984)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC.
For research use only. We do not sell to patients.
- Purity: 98.63%
- Formula: C17H21ClN4O4
- Molecular Weight:380.83
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 380.83
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Formula C17H21ClN4O4
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Color Light yellow to green yellow
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SMILES
O=C1C(C=CC(NCCCCN)=C2)=C2C(N1C(CC3)C(NC3=O)=O)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (262.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6258 mL | 13.1292 mL | 26.2584 mL | 65.6461 mL |
| 5 mM | 0.5252 mL | 2.6258 mL | 5.2517 mL | 13.1292 mL | |
| 10 mM | 0.2626 mL | 1.3129 mL | 2.6258 mL | 6.5646 mL | |
| 15 mM | 0.1751 mL | 0.8753 mL | 1.7506 mL | 4.3764 mL | |
| 20 mM | 0.1313 mL | 0.6565 mL | 1.3129 mL | 3.2823 mL | |
| 25 mM | 0.1050 mL | 0.5252 mL | 1.0503 mL | 2.6258 mL | |
| 30 mM | 0.0875 mL | 0.4376 mL | 0.8753 mL | 2.1882 mL | |
| 40 mM | 0.0656 mL | 0.3282 mL | 0.6565 mL | 1.6412 mL | |
| 50 mM | 0.0525 mL | 0.2626 mL | 0.5252 mL | 1.3129 mL | |
| 60 mM | 0.0438 mL | 0.2188 mL | 0.4376 mL | 1.0941 mL | |
| 80 mM | 0.0328 mL | 0.1641 mL | 0.3282 mL | 0.8206 mL | |
| 100 mM | 0.0263 mL | 0.1313 mL | 0.2626 mL | 0.6565 mL |
Pomalidomide-5-C4-NH2 hydrochloride Related Classifications
HY-155260 Related Classifications
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