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Cat. No.: HY-167937

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Propyl-GSK-2793660

Propyl-GSK-2793660 (compound 1) is a irreversible and covalent DPP1 inhibitor. Propyl-GSK-2793660 can be used for the study of bronchiectasis.

For research use only. We do not sell to patients.

CAS No.: 1613458-71-1
Formula: C₂₂H₃₁N₃O₃
Molecular Weight:385.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Propyl-GSK-2793660 Chemical Structure

CAS No.: 1613458-71-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Propyl-GSK-2793660 (compound 1) is a irreversible and covalent DPP1 inhibitor. Propyl-GSK-2793660 can be used for the study of bronchiectasis^[1].

IC₅₀ & Target^[1]

DPP-1

All Dipeptidyl Peptidase Isoforms :

Chemical Information

CAS No. 1613458-71-1
Molecular Weight 385.50
Formula C₂₂H₃₁N₃O₃
SMILES

O=C(C1(N)CCOCC1)N[C@@H](CC(C)C)/C=C/C(N2CCC3=C2C=CC=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Doyle K, et al. Discovery of Second Generation Reversible Covalent DPP1 Inhibitors Leading to an Oxazepane Amidoacetonitrile Based Clinical Candidate (AZD7986). J Med Chem. 2016 Oct 27;59(20):9457-9472. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Propyl-GSK-2793660

All Dipeptidyl Peptidase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Propyl-GSK-2793660 Related Classifications

HY-167937 Related Classifications