2. PROTAC Epigenetics
  3. Ligands for Target Protein for PROTAC Epigenetic Reader Domain
  4. PROTAC BRD9-binding moiety 5

PROTAC BRD9-binding moiety 5 is a selective BRD9 binder with an IC50 value of 4.20 μM, can be used for the synthesis of PROTACs. PROTAC BRD9-binding moiety 5 has antiproliferative activity against cancer cells.

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PROTAC BRD9-binding moiety 5

PROTAC BRD9-binding moiety 5 構造式

CAS 番号 : 893633-37-9

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PROTAC BRD9-binding moiety 5 関連抗体

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製品説明

PROTAC BRD9-binding moiety 5 is a selective BRD9 binder with an IC50 value of 4.20 μM, can be used for the synthesis of PROTACs. PROTAC BRD9-binding moiety 5 has antiproliferative activity against cancer cells[1].

IC50 & Target[1]

BRD9

4.2 μM (IC50)

体外実験

PROTAC BRD9-binding moiety 5 (compound 7) (0-250 μM; 48h) has antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PROTAC BRD9-binding moiety 5 関連抗体

Cell Proliferation Assay[1]

Cell Line: Jurkat, MDA-MB-231, A375 and HCT-116
Concentration: 0-250 μM
Incubation Time: 48h
Result: Exhibited antiproliferative activity against Jurkat, MDA-MB-231, A375 and HCT-116 with IC50s of 77 ± 7 μM, 125 ± 8 μM, 133 ± 5 μM and 145 ± 3 μM.
分子量

346.39

分子式

C19H18N6O
CAS 番号
SMILES

CCC1=NN=C2C(NC3=CC(NC(C)=O)=CC=C3)=NC4=C(N12)C=CC=C4
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.
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PROTAC BRD9-binding moiety 5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC BRD9-binding moiety 5893633-37-9Ligands for Target Protein for PROTACEpigenetic Reader DomainTarget Protein-binding MoietyAntiproliferativeBRD9JurkatMDA-MB-231A375 and HCT-116Inhibitorinhibitorinhibit

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製品名:
PROTAC BRD9-binding moiety 5
製品番号:
HY-143270
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