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Cat. No.: HY-13735BR

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Quinacrine hydrochloride hydrate (Standard)

Name: Quinacrine hydrochloride hydrate (Standard)
Brand: MedChemExpress
SKU: HY-13735BR
Availability: PreOrder

(Synonyms: Mepacrine hydrochloride hydrate (Standard); SN-390 hydrochloride hydrate (Standard))

Quinacrine (hydrochloride hydrate) (Standard) is the analytical standard of Quinacrine (hydrochloride hydrate). This product is intended for research and analytical applications. Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis.

For research use only. We do not sell to patients.

CAS No.: 6151-30-0
Formula: C₂₃H₃₆Cl₃N₃O₃
Molecular Weight:508.91

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Quinacrine hydrochloride hydrate (Standard) Chemical Structure

CAS No.: 6151-30-0

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 6151-30-0
Molecular Weight 508.91
Formula C₂₃H₃₆Cl₃N₃O₃
SMILES

CC(NC1=C(C=C(OC)C=C2)C2=NC3=CC(Cl)=CC=C31)CCCN(CC)CC.[H]Cl.[H]Cl.[H]O[H].[H]O[H]
Synonyms

Mepacrine hydrochloride hydrate (Standard); SN-390 hydrochloride hydrate (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Xiaoyang Wu, et al. Quinacrine Inhibits Cell Growth and Induces Apoptosis in Human Gastric Cancer Cell Line SGC-7901. Curr Ther Res Clin Exp. 2012 Feb;73(1-2):52-64. [Content Brief]

[2]. Anna Eriksson, et al. Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects. Leuk Res. 2017 Dec;63:41-46. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Quinacrine hydrochloride hydrate (Standard)

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Quinacrine hydrochloride hydrate (Standard)