(R)-Duloxetine (Standard)
(R)-Duloxetine (Standard) ((R)-LY248686 (Standard)) is the analytical standard of (R)-Duloxetine (HY-B0161C). This product is intended for research and analytical applications. (R)-Duloxetine ((R)-LY248686) is a neuronal voltage-gated sodium channel blocker with analgesic activity. (R)-Duloxetine blocks Na+ currents with higher affinity for the inactivated state than for the resting state. (R)-Duloxetine alleviates postoperative mechanical allodynia and hyperalgesia. (R)-Duloxetine exerts its effects through a local peripheral mechanism of action. (R)-Duloxetine can be used for research on postoperative (post-incisional) pain.
For research use only. We do not sell to patients.
- CAS No.: 116539-60-7
- Formula: C18H19NOS
- Molecular Weight:297.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 116539-60-7
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Molecular Weight 297.41
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Formula C18H19NOS
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SMILES
CNCC[C@@H](OC1=CC=CC2=C1C=CC=C2)C3=CC=CS3
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Synonyms
(R)-LY248686 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- (R)-Duloxetine (Standard)
- 116539-60-7
- (R)-LY248686 (Standard)
- Reference Standards
- Sodium Channel
- local peripheral mechanism of action
- analgesic activity
- rat GH3 cells
- Na+ currents
- neuronal voltage-gated sodium channel blocker
- voltage-gated Na+ channels
- rat postoperative pain model
- postoperative mechanical allodynia
- postincisional pain
- hyperalgesia
- Inhibitor
- inhibitor
- inhibit