(R)-Duloxetine
(R)-Duloxetine is a isomer of Duloxetine (HY-B0161) that causes tonic and usage-dependent impairment of neuronal Na+ channels. (R)-Duloxetine can be used in pain research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 116539-60-7
- 分子式: C18H19NOS
- 分子量:297.41
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
13.2 nM
Compound: 10a
|
Inhibition of [3H]NE reuptake at human NET expressed in HEK cells
Inhibition of [3H]NE reuptake at human NET expressed in HEK cells
|
[PMID: 19740668] |
| HEK293 | IC50 |
2.6 nM
Compound: 10a
|
Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cells
Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cells
|
[PMID: 19740668] |
| HEK293 | IC50 |
809 nM
Compound: 10a
|
Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cells
Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cells
|
[PMID: 19740668] |
化学情報
-
CAS 番号 116539-60-7
-
分子量 297.41
-
分子式 C18H19NOS
-
SMILES
CNCC[C@@H](OC1=CC=CC2=C1C=CC=C2)C3=CC=CS3
-
別名
(R)-LY248686
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)