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RdRP-IN-9

RdRP-IN-9 (Compound 6b) is a reversible covalent allosteric inhibitor of RdRp. RdRP-IN-9 demonstrates high anti-coronavirus activity, with an EC50 value of 0.68 μM against HCoV-OC43 RdRP-IN-9 exerts a more prolonged antiviral effect by reversibly acylating Cys12 in the NiRAN domain of non-structural protein 12 (nsp 12) and exhibits synergistic anti-coronavirus activity with Molnupiravir (HY-135853) .

For research use only. We do not sell to patients.

  • CAS No.: 1101848-34-3
  • Formula: C19H21NO5
  • Molecular Weight:343.37
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • RdRP-IN-9 Chemical Structure
    RdRP-IN-9 Chemical Structure
CAS No.: 1101848-34-3
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  • RdRP-IN-9 Chemical Structure
    RdRP-IN-9 Chemical Structure
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  • RdRP-IN-9