CELA2A Protein, Human (His)
Based on 1 Customer Validation
The function of the CELA2A protein as elastase goes beyond its traditional role as it not only enhances insulin signaling but also appears to play a potential physiological role in cellular glucose metabolism. This multifaceted protein circulates in the plasma and exerts regulatory effects by reducing platelet overactivation. CELA2A Protein, Human (His) is the recombinant human-derived CELA2A protein, expressed by E. coli , with N-6*His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
The function of the CELA2A protein as elastase goes beyond its traditional role as it not only enhances insulin signaling but also appears to play a potential physiological role in cellular glucose metabolism. This multifaceted protein circulates in the plasma and exerts regulatory effects by reducing platelet overactivation. CELA2A Protein, Human (His) is the recombinant human-derived CELA2A protein, expressed by E. coli , with N-6*His labeled tag.
CELA2A, identified as an elastase, possesses a distinctive role in cellular glucose metabolism and insulin signaling. This protein is known to circulate in plasma, where it plays a pivotal role in modulating platelet hyperactivation. CELA2A exhibits a dual impact on insulin dynamics, acting to both trigger insulin secretion and facilitate its degradation. Notably, the elastase enhances insulin sensitivity, emphasizing its potential physiological significance in glucose homeostasis. The multifaceted actions of CELA2A highlight its intricate involvement in the regulation of insulin signaling, platelet function, and cellular glucose metabolism.
The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-6*His
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Accession
P08217 (V29-N269)
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Molecular Construction
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N-term
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6*His
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CELA2A (V29-N269)
Accession # P08217 -
C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
CELA2A; Chymotrypsin Like Elastase Family Member 2A; Chymotrypsin Like Elastase 2A; Pancreatic Elastase IIA; ELA2A; Pancreatic Elastase 2; Chymotrypsin-Like Elastase Family Member 2A; Elastase-2A; Elastase 2A; AOMS4; Chymotrypsin-Like Elastase Family, Mem
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AA Sequence
VVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVIANN
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Predicted Molecular Mass
29.9 kDa
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Molecular Weight
Approximately 33 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of 10 mM Tris-HCl, 1 mM EDTA, 6% trehalose, pH 8.0.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US;may vary elsewhere.
Documentation
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Data Sheet (236 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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