ERH Protein, Human (N-His)

ERH proteins are involved in regulating the cell cycle and have been shown to be involved in cell division and proliferation processes. Structurally forming homodimers, it suggests potential functional significance. ERH Protein, Human (N-His) is the recombinant human-derived ERH protein, expressed by E. coli , with N-His labeled tag. The total length of ERH Protein, Human (N-His) is 104 a.a., with molecular weight of ~15 kDa.

The ERH protein is suggested to play a role in the regulation of the cell cycle, indicating its potential involvement in the intricate processes governing cell division and proliferation. Structurally, it forms homodimers, a characteristic indicative of its molecular arrangement and potential functional significance. Moreover, ERH interacts with POLDIP3 and is a component of the methylosome, a 20S complex that includes CLNS1A/pICln, PRMT5/SKB1, WDR77/MEP50, PRMT1, and ERH. This complex, as identified in studies, implies ERH's participation in protein methylation processes. Additionally, ERH interacts with CHTOP, further suggesting its engagement in diverse molecular pathways and highlighting its multifaceted role within cellular mechanisms.

Human

E. coli

N-His

P84090 (M1-K104)

2079  [NCBI]

Approximately 15 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 300mM NaCl, 5% trehalose, 5% mannitol and 0.01% Tween80, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.