2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interferon & Receptors
  5. IFN-alpha
  6. Interferon alpha-B
  7. IFN-alpha B/IFNA8 Protein, Human (HEK293, His)

IFN-alpha B/IFNA8 Protein, Human (HEK293, His)

Cat. No.: HY-P73860
Handling Instructions

IFN-alpha B/IFNA8 Protein, synthesized by macrophages, displays potent antiviral activities. It stimulates the production of essential enzymes—a protein kinase and an oligoadenylate synthetase—that are pivotal in cellular defense against viral infections. IFN-alpha B/IFNA8 Protein, Human (HEK293, His) is the recombinant human-derived IFN-alpha B/IFNA8 protein, expressed by HEK293 , with C-His labeled tag. The total length of IFN-alpha B/IFNA8 Protein, Human (HEK293, His) is 166 a.a., with molecular weight of ~28 kDa.

For research use only. We do not sell to patients.

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Description

IFN-alpha B/IFNA8 Protein, synthesized by macrophages, displays potent antiviral activities. It stimulates the production of essential enzymes—a protein kinase and an oligoadenylate synthetase—that are pivotal in cellular defense against viral infections. IFN-alpha B/IFNA8 Protein, Human (HEK293, His) is the recombinant human-derived IFN-alpha B/IFNA8 protein, expressed by HEK293 , with C-His labeled tag. The total length of IFN-alpha B/IFNA8 Protein, Human (HEK293, His) is 166 a.a., with molecular weight of ~28 kDa.
Background

IFN-alpha B/IFNA8 Protein, produced by macrophages, exhibits potent antiviral activities. It stimulates the production of two crucial enzymes: a protein kinase and an oligoadenylate synthetase. These enzymes play crucial roles in the cellular defense against viral infections.
Species

Human
Source

HEK293
Tag

C-His
Accession

P32881 (C24-E189)
Gene ID
Molecular Construction
N-term
IFNA8 (C24-E189)
Accession # P32881
His
C-term
Synonyms
IFNA8; IFN-alpha 8; IFN-alpha B2; Interferon alpha-8; Interferon alpha-B
Molecular Weight

Approximately 28 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

IFN-alpha B/IFNA8 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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IFN-alpha B/IFNA8 Protein, Human (HEK293, His)
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