PRKD3/nPKC nu Protein, Human (Active, sf9, GST)
PRKD3/nPKC nu protein acts as a mediator in the conversion of transient diacylglycerol (DAG) signals into sustained physiological effects, functioning downstream of PKC.Additionally, it plays a crucial role in conferring resistance to oxidative stress, demonstrating its involvement in cellular responses to environmental challenges.PRKD3/nPKC nu Protein, Human (sf9, GST) is the recombinant human-derived PRKD3/nPKC nu protein, expressed by Sf9 insect cells , with GST labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
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Biological Activity
Description
PRKD3/nPKC nu protein acts as a mediator in the conversion of transient diacylglycerol (DAG) signals into sustained physiological effects, functioning downstream of PKC.Additionally, it plays a crucial role in conferring resistance to oxidative stress, demonstrating its involvement in cellular responses to environmental challenges.PRKD3/nPKC nu Protein, Human (sf9, GST) is the recombinant human-derived PRKD3/nPKC nu protein, expressed by Sf9 insect cells , with GST labeled tag.
Background
Protein kinase D3 (PRKD3), also known as novel protein kinase C nu (nPKC nu), serves a crucial role in cellular signaling by converting transient diacylglycerol (DAG) signals into sustained physiological effects, acting downstream of protein kinase C (PKC). This kinase's ability to modulate signaling cascades suggests its involvement in diverse cellular processes that rely on prolonged responses to diacylglycerol. Furthermore, PRKD3/nPKC nu has been implicated in conferring resistance to oxidative stress, indicating its potential role in cellular defense mechanisms against reactive oxygen species and related stressors (By similarity). The multifaceted functions of PRKD3/nPKC nu underscore its importance in signal transduction, suggesting its contribution to cellular adaptation and survival in response to various environmental challenges.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag GST
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Accession
O94806 (S2-P890)
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Protein Length
Full Length
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Synonyms
PRKD3; PKD3; Prev. PRKCN; Protein Kinase C, Nu; EPK2; Protein Kinase C; Serine/Threonine-Protein Kinase D3; NPKC-NU; Protein Kinase C Nu Type; NPKC-Nu; Protein Kinase EPK2; PKC-NU; Protein Kinase D3; Serine/Threonine-Protein Kinase
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AA Sequence
SANNSPPSAQKSVLPTAIPAVLPAASPCSSPKTGLSARLSNGSFSAPSLTNSRGSVHTVSFLLQIGLTRESVTIEAQELSLSAVKDLVCSIVYQKFPECGFFGMYDKILLFRHDMNSENILQLITSADEIHEGDLVEVVLSALATVEDFQIRPHTLYVHSYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRKRRLSNVSLPGPGLSVPRPLQPEYVALPSEESHVHQEPSKRIPSWSGRPIWMEKMVMCRVKVPHTFAVHSYTRPTICQYCKRLLKGLFRQGMQCKDCKFNCHKRCASKVPRDCLGEVTFNGEPSSLGTDTDIPMDIDNNDINSDSSRGLDDTEEPSPPEDKMFFLDPSDLDVERDEEAVKTISPSTSNNIPLMRVVQSIKHTKRKSSTMVKEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQNESGSKYYKEIPLSEILRISSPRDFTNISQGSNPHCFEIITDTMVYFVGENNGDSSHNPVLAATGVGLDVAQSWEKAIRQALMPVTPQASVCTSPGQGKDHKDLSTSISVSNCQIQENVDISTVYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDINDQIQNAAFMYPPNPWREISGEAIDLINNLLQVKMRKRYSVDKSLSHPWLQDYQTWLDLREFETRIGERYITHESDDARWEIHAYTHNLVYPKHFIMAPNPDDMEEDP
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Predicted Molecular Mass
126.7 kDa
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Purity
≥ 85%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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