SLITRK1 Protein, Human (HEK293, His)

The SLITRK1 protein is critical in synaptogenesis, promoting excitatory synaptic differentiation and synaptic maturation. Its effects extend to enhancing the growth of neuronal dendrites, emphasizing its importance in neuronal development. SLITRK1 Protein, Human (HEK293, His) is the recombinant human-derived SLITRK1 protein, expressed by HEK293 , with C-His labeled tag.

SLITRK1 plays a crucial role in synaptogenesis, actively promoting the differentiation of excitatory synapses, as evidenced by its involvement in synaptic maturation. Additionally, SLITRK1 contributes to the enhancement of neuronal dendrite outgrowth, underscoring its significance in neuronal development and morphology. The protein is capable of forming homodimers, with this dimerization process specifically dependent on the presence of the repeat LRR 2 domain. Moreover, SLITRK1 interacts with various members of the 14-3-3 protein family, including YWHAB, YWHAE, YWHAG, YWHAH, SFN, YWHAQ, and YWHAZ, suggesting potential regulatory roles and cellular functions mediated by these interactions.

Human

HEK293

C-His

Q96PX8 (N18-S616)

114798  [NCBI]

Partial

NVTGDVCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAPTSQFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVFQYVPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNETTEQDLCPLKNRVDSSLPAPPAQEETFAPGPLPTPFKTNGQEDHATPGSAPNGGTKIPGNWQIKIRPTAAIATGSSRNKPLANSLPCPGGCSCDHIPGSGLKMNCNNRNVSSLADLKPKLSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLMSDLKCETPVNFFRKDFMLLSNDEICPQLYARISPTLTSHSKNSTGLAETGTHSNSYLDTSRVS

105-115 kDa

≥ 95%, as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.