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  4. SMARCA2 Protein, Human (P.pastoris, His)

SMARCA2 Protein, Human(P.pastoris, His) is a subunit of the Switch/Sucrose non-fermenting (SWI/SNF) complex, which play an important role in chromatin remodeling and regulation of downstream gene expression in neural development.

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Description

SMARCA2 Protein, Human(P.pastoris, His) is a subunit of the Switch/Sucrose non-fermenting (SWI/SNF) complex, which play an important role in chromatin remodeling and regulation of downstream gene expression in neural development.
Background

SMARCA2 is located on chromosome 9p24.3, and it encodes a component of SWI/SNF complexes. The SMARCA2 protein is a subunit of the SWI/SNF complexes which participate in chromatin remodeling in an ATPase-dependent manner[1]. SMARCA2 also shows frequent alterations in rhabdoid tumors, ovarian clear cell carcinomas (OCCCs), and small-cell carcinoma of the ovary, hyper-calcemic type (SCCOHT)[2].
Species

Human
Source

P. pastoris
Tag

N-6*His
Accession

P51531 (S700-F1216)
Gene ID
Molecular Construction
N-term
6*His
SMARCA2 (S700-F1216)
Accession # P51531
C-term
Protein Length

Partial
Synonyms
BAF190B, Probable global transcription activator SNF2L2
AA Sequence

SYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAF

Predicted Molecular Mass
61.7kDa
Purity

≥ 90%, as determined by reducing SDS-PAGE.
Documentation
SDS (251 KB)

COA (219 KB)

Handling Instructions (2659 KB)
References

SMARCA2 Protein, Human (P.pastoris, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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