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Tetranectin/CLEC3B Protein, Human (181a.a, HEK293, His)

Cat. No.: HY-P7815
COA Handling Instructions

Tetranectin/CLEC3B protein exhibits binding to plasminogen and isolated kringle 4, suggesting potential roles in exocytosis-related molecule packaging and ocular physiology. Its homotrimeric structure emphasizes a propensity for trimeric complexes, highlighting the multifaceted nature of Tetranectin/CLEC3B in diverse molecular interactions and cellular processes. Tetranectin/CLEC3B Protein, Human (181a.a, HEK293, His) is the recombinant human-derived Tetranectin/CLEC3B protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Tetranectin/CLEC3B Protein, Human (181a.a, HEK293, His) is 181 a.a., with molecular weight of ~20.0 kDa.

For research use only. We do not sell to patients.

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Description

Tetranectin/CLEC3B protein exhibits binding to plasminogen and isolated kringle 4, suggesting potential roles in exocytosis-related molecule packaging and ocular physiology. Its homotrimeric structure emphasizes a propensity for trimeric complexes, highlighting the multifaceted nature of Tetranectin/CLEC3B in diverse molecular interactions and cellular processes. Tetranectin/CLEC3B Protein, Human (181a.a, HEK293, His) is the recombinant human-derived Tetranectin/CLEC3B protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Tetranectin/CLEC3B Protein, Human (181a.a, HEK293, His) is 181 a.a., with molecular weight of ~20.0 kDa.

Background

The Tetranectin/CLEC3B protein demonstrates binding capabilities to plasminogen and isolated kringle 4. It is implicated in potential roles related to the packaging of molecules designated for exocytosis, suggesting a function in cellular secretion processes. Additionally, Tetranectin/CLEC3B plays a role in retinal function, indicating its involvement in ocular physiology. Structurally, it forms homotrimers, emphasizing its tendency to exist as trimeric complexes. The diverse binding capacities and proposed functions underscore the multifaceted nature of Tetranectin/CLEC3B, implicating its involvement in various molecular interactions and cellular processes.

Species

Human

Source

HEK293

Tag

C-6*His

Accession

AAH11024.1 (E22-V202)

Gene ID
Molecular Construction
N-term
CLEC3B (E22-V202)
Accession # AAH11024.1
6*His
C-term
Synonyms
rHuTetranectin/ CLEC3B, His; Tetranectin; TN; C-Type Lectin Domain Family 3 Member B; Plasminogen Kringle 4-Binding Protein; CLEC3B; TNA
AA Sequence

EPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV

Molecular Weight

Approximately 20.0 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE

Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

Tetranectin/CLEC3B Protein, Human (181a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Tetranectin/CLEC3B Protein, Human (181a.a, HEK293, His)
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HY-P7815
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