1. Apoptosis
  2. RIP kinase
  3. RIPK1-IN-13

RIPK1-IN-13 (Compound 8) is a potent inhibitor of RIPK1 with an IC50 value of 1139 nM. RIPK1-IN-13 blocks the activation of the necroptosis pathway via the inhibition of RIPK1. RIPK1-IN-13 has the potential for the research of inflammation diseases.

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RIPK1-IN-13

RIPK1-IN-13 화학구조

CAS No. : 1574547-67-3

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제품 설명

RIPK1-IN-13 (Compound 8) is a potent inhibitor of RIPK1 with an IC50 value of 1139 nM. RIPK1-IN-13 blocks the activation of the necroptosis pathway via the inhibition of RIPK1. RIPK1-IN-13 has the potential for the research of inflammation diseases[1].

분자량

397.85

화학식

C21H20ClN3O3

CAS No.
SMILES

O=C(N1CCC2(NC(N(C2=O)CC3=CC(Cl)=CC=C3)=O)CC1)C4=CC=CC=C4

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
RIPK1-IN-13
Cat. No.:
HY-146757
수량:
MCE Japan Authorized Agent: