1574547-67-3
1574547-67-3
Chemical Structure
RIPK1-IN-13
- CAS No.: 1574547-67-3
- Formula:C21H20ClN3O3
- Molecular Weight:397.85
IUPAC Name: 8-benzoyl-3-(3-chlorobenzyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
InChIKey: IMNMERDXXWBEER-UHFFFAOYSA-N
SMILES: O=C(N1CCC2(NC(N(C2=O)CC3=CC(Cl)=CC=C3)=O)CC1)C4=CC=CC=C4
Biological Activity: RIPK1-IN-13 (Compound 8) is a potent inhibitor of RIPK1 with an IC50 value of 1139 nM. RIPK1-IN-13 blocks the activation of the necroptosis pathway via the inhibition of RIPK1. RIPK1-IN-13 has the potential for the research of inflammation diseases[1].
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RIPK1-IN-13 | RIPK1-IN-13 (Compound 8) is a potent inhibitor of RIPK1 with an IC50 value of 1139 nM. RIPK1-IN-13 blocks the activation of the necroptosis pathway via the inhibition of RIPK1. RIPK1-IN-13 has the potential for the research of inflammation diseases. | |||||||||||||||||||||
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