1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Histamine Receptor
  3. ROS 234

ROS 234 is a potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 diaplays poor central access.

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ROS 234

ROS 234 화학구조

CAS No. : 184576-87-2

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제품 설명

ROS 234 is a potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 diaplays poor central access[1][2].

IC50 & Target[1]

rat H3 receptor

8.90 (pKi)

In Vivo

ROS 234 centrally injected, significantly shortens pentobarbital narcosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

241.29

화학식

C13H15N5

CAS No.
SMILES

C1(NCCCC2=CN=CN2)=NC3=CC=CC=C3N1

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

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상품명:
ROS 234
Cat. No.:
HY-107563
수량:
MCE Japan Authorized Agent: