(S)-Desamino lenalidomide-2,7-diazaspiro[3.5]nonane
(S)-Desamino lenalidomide-2,7-diazaspiro[3.5]nonane is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
For research use only. We do not sell to patients.
- Formula: C20H24N4O3
- Molecular Weight:368.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
![(S)-Desamino lenalidomide-2,7-diazaspiro[3.5]nonane Chemical Structure](https://file.medchemexpress.com/product_pic/hy-w998343.gif "Click to View (S)-Desamino lenalidomide-2,7-diazaspiro[3.5]nonane Chemical Structure")
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 368.43
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Formula C20H24N4O3
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SMILES
O=C(N1)[C@H](CCC1=O)N(C2=O)CC3=C2C=CC(N4CCC5(CNC5)CC4)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S)-Desamino lenalidomide-2,7-diazaspiro[3.5]nonane Related Classifications
HY-W998343 Related Classifications
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