(S,R,S)-AHPC-Me-C8-NHS ester
Based on 1 Customer Validation
The (S,R,S)-AHPC-Me-C8-NHS ester is an E3 ubiquitin ligase VHL ligand, used to recruit the VHL protein. The (S,R,S)-AHPC-Me-C8-NHS ester can be linked to the target protein ligand through a linker to form a PROTAC.
For research use only. We do not sell to patients.
- Purity: 99.89%
- Formula: C37H51N5O8S
- Molecular Weight:725.89
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
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VHL |
Chemical Information
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Appearance Solid
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Molecular Weight 725.89
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Formula C37H51N5O8S
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Color White to off-white
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SMILES
CC(C)([C@H](NC(CCCCCCCCC(ON1C(CCC1=O)=O)=O)=O)C(N2[C@@H](C[C@H](C2)O)C(N[C@@H](C)C3=CC=C(C=C3)C4=C(N=CS4)C)=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 50 mg/mL (68.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (245 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3776 mL | 6.8881 mL | 13.7762 mL | 34.4405 mL |
| 5 mM | 0.2755 mL | 1.3776 mL | 2.7552 mL | 6.8881 mL | |
| 10 mM | 0.1378 mL | 0.6888 mL | 1.3776 mL | 3.4440 mL | |
| 15 mM | 0.0918 mL | 0.4592 mL | 0.9184 mL | 2.2960 mL | |
| 20 mM | 0.0689 mL | 0.3444 mL | 0.6888 mL | 1.7220 mL | |
| 25 mM | 0.0551 mL | 0.2755 mL | 0.5510 mL | 1.3776 mL | |
| 30 mM | 0.0459 mL | 0.2296 mL | 0.4592 mL | 1.1480 mL | |
| 40 mM | 0.0344 mL | 0.1722 mL | 0.3444 mL | 0.8610 mL | |
| 50 mM | 0.0276 mL | 0.1378 mL | 0.2755 mL | 0.6888 mL | |
| 60 mM | 0.0230 mL | 0.1148 mL | 0.2296 mL | 0.5740 mL |
(S,R,S)-AHPC-Me-C8-NHS ester Related Classifications
HY-185142 Related Classifications
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