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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
AC4
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "AC4" in MCE Product Catalog:
Cat. No.: HY-161913
Target:
Research Areas:
AC-4-248 is an atypical non-competitive dopamine transporter (DAT) inhibitor and reduces the potency of cocaine to inhibit DAT. AC-4-248 is a non-selective inhibitor of SLC6 transporters with IC50 values for hDAT, hSERT, and hNET of 45.5 μM, 96.2 μM, and 250 μM, respectively .
Cat. No.: HY-P4688
CAS No.: 1926163-83-8
Target:
Research Areas:
Cat. No.: HY-RS00330
Target:
Research Areas:
ADCY4 Human Pre-designed siRNA Set A contains three designed siRNAs for ADCY4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W768178
Synonyms: D-Glucosamine Hydrochloride-1,2-13C2
Cat. No.: HY-174968A
Synonyms: 4-Arm-PEG5000-ACrylate
Cat. No.: HY-W699962
CAS No.: 137766-83-7
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Ac4GlcNAcF3 is a cell-permeable glycomimetic that can be recognized and utilized by OGT and is resistant to hydrolysis by OGA. GlcNAcF3, the active metabolite of Ac4GlcNAcF3, can be recognized by OGT as a substrate for peptide modification. Ac4GlcNAcF3 upregulates the level of cellular O-GlcNAc modification. Ac4GlcNAcF3 can be used in studies related to glycosylation regulation .
Cat. No.: HY-W728531R
CAS No.: 1213701-11-1
Target:
Reference Standards Biochemical Assay Reagents p38 MAPK Potassium Channel Mitochondrial Metabolism
Research Areas:
Ac4ManNAz (Standard) is the analytical standard of Ac4ManNAz (HY-W728531). This product is intended for research and analytical applications. Ac4ManNAz can be taken up by cells and is an azide-containing metabolic glycoprotein labeling reagent that selectively modifies proteins. Commonly used for cell labeling, tracKing and proteomic analysis. Ac4ManNAz contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Ac4ManNAz can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Cat. No.: HY-118297R
CAS No.: 361154-30-5
Research Areas:
Ac4ManNAz (80% α isomer) (Standard) is the analytical standard of Ac4ManNAz (80% α isomer) (HY-118297). This product is intended for research and analytical applications. Ac4ManNAz is an azido-containing metabolic glycoprotein labeling reagent. Ac4ManNAz can be used to selectively modify proteins. Ac4ManNAz can be used in cell labeling, tracKing and proteomic analysis . Ac4ManNAz is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-W415799
CAS No.: 1658458-26-4
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(2S)-Ac4GalNAl can be used for the identification and characterization of specific surface groups of glycoproteins. The alkyne groups can react with azides via copper-catalyzed Click Chemistry. The acetyl groups on the glucose allow for easier penetration through the cell membrane.
Cat. No.: HY-N9459R
CAS No.: 1078691-95-8
Synonyms: D-Glucosamine Hydrochloride (Standard)
Category:
Target:
Cat. No.: HY-W766388
Synonyms: D-Glucosamine Hydrochloride-13C6
Cat. No.: HY-174968C
Synonyms: 4-Arm-PEG20000-ACrylate
Cat. No.: HY-P72328
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: H2AC4; Histone H2A Type 1-B/E; Prev. HIST1H2AB; Histone H2A/M; Prev. H2AFM; HIST1H2AE; H2A/M; Histone H2A/A; Histone Cluster 1 H2A Family Member B; Histone H2A.2; H2A Histone Family, Member M; Histone H2A; Histone Cluster 1, H2ab; H2AFA; H2A Clustered His
Species:
Human
Source:
E. coli
Cat. No.: HY-183618
Target:
Research Areas:
DW-229 is a PROTAC degrader derived from Deferiprone (HY-B0568), targeting Fe(II)/α‑ketoglutarate‑dependent histone lysine demethylases (KDMs). DW-229 degrades KDM2A, KDM3A, KDM5B, KDM4A‑C, KDM5C, KDM6B in breast cancer cells. DW-229 shows IC50 < 0.5 μM against MCF‑7 cells and IC50 of 8.87 μM against MDA‑MB‑231 cells, with high cancer cell selectivity. DW-229 can be used for the research of breast cancer, liver cancer, prostate cancer, lung cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
