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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
BACE2
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "BACE2" in MCE Product Catalog:
Cat. No.: HY-P75588
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE2; Memapsin-1; Prev. AEPLC; Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme 2; ALP56; Beta-Site Amyloid Precursor Protein Cleaving Enzyme 2; ASP1; Down Syndrome Region Aspartic Protease; DRAP; Transmembrane Aspartic Proteinase Asp1; Aspart
Species:
Mouse
Source:
HEK293
Cat. No.: HY-100182A
CAS No.: 1310349-35-9
Target:
Research Areas:
BACE1-IN-1 hydrochloride is an orally active, blood-brain barrier penetrant dual-target inhibitor of BACE1/2, with IC50 values of 23 nM and 24 nM against human BACE1 and BACE2, respectively. BACE1-IN-1 hydrochloride reduces cerebral Aβ40 levels in mice. BACE1-IN-1 hydrochloride can be used in studies related to Alzheimer's disease and type 2 diabetes [2].
Cat. No.: HY-100182R
CAS No.: 1310347-50-2
BACE1-IN-1 (Standard) is the analytical standard of BACE1-IN-1 (HY-100182). This product is intended for research and analytical applications. BACE1-IN-1 is an orally active, blood-brain barrier penetrant dual-target inhibitor of BACE1/2, with IC50 values of 23 nM and 24 nM against human BACE1 and BACE2, respectively. BACE1-IN-1 reduces cerebral Aβ40 levels in mice. BACE1-IN-1 can be used in studies related to Alzheimer's disease and type 2 diabetes [2].
Cat. No.: HY-10472R
CAS No.: 1194044-20-6
Target:
Research Areas:
LY2811376 (Standard) is the analytical standard of LY2811376 (HY-10472). This product is intended for research and analytical applications. LY2811376 is the first orally available non-peptidic β-secretase (BACE1) inhibitor with IC50 of 239 nM-249 nM, that acts to decrease Aβ secretion with EC50 of 300 nM, and demonstrates to have 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including cathepsin D, pepsin, or renin.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
