27 Results for "

GRPR

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "GRPR" in MCE Product Catalog:

Cat. No.: HY-180434
CAS No.: 2077238-49-2
Target:  

Bombesin Receptor

Research Areas:  

Cancer

GRPR antagonist-3 (compound (S)-1m) is a potent GRPR antagonist with an IC50 of 121 nM. GRPR antagonist-3 is stable in rat plasma and towards microsomal oxidative metabolism in vitro. GRPR antagonist-3 can be radiolabeled with fluorine-18 for PET imaging .
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Cat. No.: HY-P790077
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GRPR; BRS2; Gastrin Releasing Peptide Receptor; BB2; Gastrin-Releasing Peptide Receptor; Bombesin Receptor 2; GRP-Preferring Bombesin Receptor; GRP-R; BB2R
Species:  
Human
Source:  
E. coli Cell-free
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Cat. No.: HY-RS23613
Research Areas:  

Others

Grpr Rat Pre-designed siRNA Set A contains three designed siRNAs for Grpr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N2600R
CAS No.: 76472-87-2
Kuwanon H (Standard) is the analytical standard of Kuwanon H. This product is intended for research and analytical applications. Kuwanon H is a selective non-peptide bombesin receptor antagonist and platelet activation inhibitor. Kuwanon H also acts as a specific antagonist of GRP-preferring receptors, with a Ki value of 290 nM for mouse GRP-R and 6500 nM for rat NMB-R. Kuwanon H inhibits the phosphorylation of AKT, mTOR, ERK, cPLA2 and p38, and upregulates TRIB3. It induces endoplasmic reticulum stress, apoptosis and autophagosome formation. Kuwanon H blocks calcium mobilization, mitogenic signaling, DNA synthesis, dense granule secretion, thromboxane A2 generation and integrin αIIb/β3 activity. It inhibits collagen-induced platelet aggregation and fibronectin adhesion, and delays clot retraction. Kuwanon H inhibits melanoma cell growth in vitro and in vivo, and enhances the sensitivity of melanoma cells to CDDP. It can be used in research related to melanoma, small cell lung cancer and thrombosis .
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Cat. No.: HY-P11768
CAS No.: 721937-56-0
Target:  

Bombesin Receptor

Research Areas:  

Cancer

AMBA is a gastrin-releasing peptide receptor (GRPR, BB2, BRS-2) ligand. AMBA binds to GRPR with high specificity and high affinity, and undergoes receptor-mediated endocytosis, which retains the conjugated radiometal in target cells. AMBA is applicable for the research of prostate cancer .
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Cat. No.: HY-P11917
LF1 is a gastrin-releasing peptide receptor (GRPR) antagonist. LF1 can be stably radiolabeled with gallium- 68, indium- 111, and lutetium- 177. Radiolabeled LF1 can be used for high-contrast SPECT/CT imaging. LF1 is applicable to prostate cancer-related research .
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Cat. No.: HY-P11769
CAS No.: 1186600-65-6
Synonyms: RM2
Target:  

CGRP Receptor

Research Areas:  

Cancer

RM2 is a GRPr antagonist. RM2 selectively binds to GRPr, blocks agonist-induced receptor internalization, and inhibits agonist-triggered intracellular calcium mobilization. RM2 can be used in studies related to prostate cancer .
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