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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
88 Results for "
Insecticidal Agent
" in MedChemExpress (MCE) Product Catalog:
Products (88)
88 Results for "Insecticidal Agent" in MCE Product Catalog:
Synonyms: IKI220-15N18O
Domaines de recherche:
Flonicamid- 15N, 18O (IKI220- 15N, 18O) is the 18O
, 15N-labeled Flonicamid (HY-119649). Flonicamid (IKI220) is an antifeedant Insecticide active against Hemiptera, Thysanoptera, and piercing-sucking pests including aphids of all species, developmental stages and morphs. Flonicamid inhibits the inward rectifier potassium channel NlKir1, blocking stylet penetration, salivation, sap feeding, honeydew secretion, and fluid secretion by isolated Malpighian tubules. Flonicamid reduces renal excretory function in female Culex pipiens pallens. Flonicamid rapidly disrupts insect feeding behavior without neurotoxic poisoning symptoms, induces irreversible starvation, and increases the mortality of nymph progeny of adult aphids exposed to this agent .
Cat. No.: HY-149864
Target:
Domaines de recherche:
Insecticidal agent 3 is a multichitinase inhibitors, belongs to insect growth regulators (IGRs)，with Kis of 0.8μM, 11.9 μM, and 2.3 μM for Of ChtI, Of ChtII, and Of Chi-h, respectively. Insecticidal agent 3 exhibits insecticidal activity against two lepidopteran pests by interfering with normal insect growth and molting .
Cat. No.: HY-P10390
CAS No.: 1798816-86-0
Cat. No.: HY-168570
CAS No.: 3046365-94-7
Insecticidal agent 16 (compound A21) is a potent insecticidal agent. Insecticidal agent 16 shows insecticidal activities against Plutella xylostella and Spodoptera frugiperda with LC50 values of 1.2 and 13.2 µg/mL, respectively .
Cat. No.: HY-172953
Insecticidal agent 24 is an orally active pyridylspiroindoline frontrunner. Insecticidal agent 24 has antiplasmodial activity (Pf NF54 IC50: 0.08 μM). Insecticidal agent 24 inhibits hERG activity (IC50: 6.5 μM). Insecticidal agent 24 reduces parasitemia in a humanized immunodeficient NSG mouse Plasmodium falciparum infection model .
Cat. No.: HY-173413
CAS No.: 3082443-45-3
Domaines de recherche:
Insecticidal agent 21 (Compound 6) is an insecticide that is effective against Culex pipiens larvae (LC50: 0.4 μg/mL). Insecticidal agent 21 achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors (nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR)). Insecticidal agent 21 has a strong insecticidal effect and can be used in the development of new insecticides to address the problem of mosquito resistance to traditional insecticides .
Cat. No.: HY-168840
Target:
Domaines de recherche:
Insecticidal agent 17 (compound 31) is an insecticidal agent against Plutella xylostella Linnaeus with an LC50 value of 0.759 mg/mL .
Cat. No.: HY-142916
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Domaines de recherche:
Insecticidal agent 1 displays more potent insecticidal activity than obacunone and toosendanin.
Cat. No.: HY-158327
Target:
Domaines de recherche:
Insecticidal agent 9 (Compound I-17) is an insecticide with good insecticidal activity. Insecticidal agent 9 has LC50 values of 93.32 mg/L and 114.79 mg/L against Plutella xylostella and Ostrinia furnacalis respectively, and exhibits a mortality rate of up to 86.1% against Spodoptera frugiperda at a concentration of 500 mg/L. Insecticidal agent 9 can act simultaneously on the ecdysone receptor (EcR) and three chitinases (OfChtI, OfChtII, and OfChi-h), demonstrating good binding activity (to EcR) and inhibitory rates (to the three chitinases). Insecticidal agent 9 can be used in research for pest management .
Cat. No.: HY-162279
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Domaines de recherche:
Insecticidal agent 8 ((S)-4a-14) is an insecticidal agent that has significant selective biological against Aphis craccivora Koch and Plutella xylostella .
Cat. No.: HY-149697
CAS No.: 1699760-76-3
Insecticidal agent 6 (Compound Im) is an insect ryanodine receptors (RyRs) inhibitor, with an EC50 value of 0.6308 µM against S. frugiperda RyRs. Insecticidal agent 6 has excellent insecticidal activity against lepidopteran pests and can be used for research on pests and diseases .
Cat. No.: HY-163157
CAS No.: 2951079-77-7
Insecticidal agent 7 (Compound 21m) is an insecticide that targets the insect ryanodine receptors (RyRs) with a LC50 of 0.0937 mg/L for the Plutella xylostella. Insecticidal agent 7 (Compound 21m) exhibits good selectivity and low toxicity towards non-target organisms .
Cat. No.: HY-156256
CAS No.: 2989908-99-6
Insecticidal agent 4 (compound IA-8) is an aryl isoxazoline derivative with insecticidal activity against M. separate .
Cat. No.: HY-176042
Target:
Domaines de recherche:
Insecticidal agent 22 (Compound A13) is an insecticide, with LC50s of 1.4 and 9.9 μg/mL for diamondback moth (Plutella xylostella) and fall armyworm (Spodoptera frugiperda), respectively. Insecticidal agent 22 can be used as a low-toxicity alternative to Fluralaner (HY-16973) .
Cat. No.: HY-157162
CAS No.: 3021587-00-5
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Domaines de recherche:
Insecticidal agent 5 (compound 8) is an AChE-targeting insecticide with an LD50 of 27.65 ppm against the cotton leafworm Spodoptera littoralis .
Cat. No.: HY-163776
CAS No.: 3007662-84-9
Insecticidal agent 13 (compound A15) is a phenylpyrazole derivative with insecticidal and acaricidal activities, which can be used in the research of agricultural pest control .
Cat. No.: HY-172794
CAS No.: 3031757-63-5
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Insecticidal agent 23 (compound 17) has antischistosomal efficacy and low toxicity. Insecticidal agent 23 exhibits potent in vitro activity against adult S. japonicum, with an LC50 (72 h) value of 25.31 μM.
Cat. No.: HY-163560
CAS No.: 3026314-21-3
Insecticidal agent 10 (Compound 8c) is an inhibitor for chitinase, which inhibits OfChi-h and OfChtI with IC50 of 1.51 and 9.21 nM, respectively. Insecticidal agent 10 inhibits growth of Ostrinia furnacalis with LC50 of 22.14 mg/L .
Cat. No.: HY-168918
Domaines de recherche:
Insecticidal agent 19 (Compound 7b) exhibits antimalarial activity by inhibiting dihydrofolate
reductase-thymidylate synthase (DHFR-TS) and pteridine reductase 1 (PTR1) through the folic acid metabolic pathway. Insecticidal agent 19 inhibits Leishmania major promastigote and amastigote with IC50 of 1.43 μM and 3.78 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
