Insecticidal agent 19
Insecticidal agent 19 (Compound 7b) exhibits antimalarial activity by inhibiting dihydrofolate reductase-thymidylate synthase (DHFR-TS) and pteridine reductase 1 (PTR1) through the folic acid metabolic pathway. Insecticidal agent 19 inhibits Leishmania major promastigote and amastigote with IC50 of 1.43 μM and 3.78 μM.
For research use only. We do not sell to patients.
- Formula: C26H15ClN4O6
- Molecular Weight:514.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Description
Chemical Information
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Molecular Weight 514.87
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Formula C26H15ClN4O6
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SMILES
O=C(C1N2N=C(C=C2C3=CC=C(C=C3)Cl)C4=C(C5=C(OC4=O)C=CC=C5)O)NC(C=C6)=C1C=C6[N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Insecticidal agent 19 Related Classifications
HY-168918 Related Classifications
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