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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
RIP3
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "RIP3" in MCE Product Catalog:
Cat. No.: HY-P71855
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RIPK3; RIP-3; Receptor Interacting Serine/Threonine Kinase 3; Receptor-Interacting Serine-Threonine Kinase 3; RIP3; Receptor Interacting Protein 3; Receptor-Interacting Serine/Threonine-Protein Kinase 3; Receptor-Interacting Protein 3; RIP-Like Protein Ki
Species:
Human
Source:
P. pastoris
Cat. No.: HY-RS11999
Research Areas:
Ripk3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ripk3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12000
Research Areas:
Ripk3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ripk3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08629
Target:
Research Areas:
MPRIP Human Pre-designed siRNA Set A contains three designed siRNAs for MPRIP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21654
Target:
Research Areas:
Mprip Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mprip gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-100904A
CAS No.: 72583-92-7
Synonyms: 2 BFI free base
Target:
Research Areas:
RX 801077 (2 BFI free base) is a selective imidazoline I2 receptor (I2R) agonist with a Ki value of 70.1 nM. RX 801077 shows anti-inflammation and neuroprotection. RX 801077 has the potential for the research of traumatic brain injury (TBI) .
Cat. No.: HY-183538
Target:
Necroptosis Reactive Oxygen Species (ROS) Mitochondrial Metabolism Mixed Lineage Kinase RIP kinase
Research Areas:
Necroptosis inducer 2 is a necroptosis inducer and copper chelator. Necroptosis inducer 2 chelates intracellular free copper ions, disrupts redox homeostasis, elevates ROS levels, disrupts mitochondrial membrane potential, and induces cancer cell necroptosis. Necroptosis inducer 2 upregulates the necroptosis markers p-MLKL and p-RIP3 expression. Necroptosis inducer 2 exhibits anti-tumor activity in mice. Necroptosis inducer 2 can be used for the research of cancer, such as triple-negative breast cancer .
Cat. No.: HY-101872AR
CAS No.: 2703752-81-0
Target:
Research Areas:
GSK-872 hydrochloride (Standard) is the analytical standard of GSK-872 hydrochloride (HY-101872A). This product is intended for research and analytical applications. GSK-872 hydrochloride is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. GSK-872 hydrochloride decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury [3].
Cat. No.: HY-101872R
CAS No.: 1346546-69-7
Target:
Research Areas:
GSK-872 (Standard) is the analytical standard of GSK-872 (HY-101872). This product is intended for research and analytical applications. GSK-872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. GSK-872 decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury [3].
Cat. No.: HY-P810537
Synonyms: Receptor interacting protein 3; Receptor interacting serine threonine kinase 3; Receptor interacting serine/threonine protein kinase 3; Receptor-interacting protein 3; Receptor-interacting serine/threonine-protein kinase 3; RIP 3; RIP like protein kinase 3; RIP-3; RIP-like protein kinase 3; RIPK 3
Cat. No.: HY-P810290
Synonyms: Receptor-interacting serine/threonine-protein kinase 3, RIPK3,RIP3
Cat. No.: HY-P810290A
Synonyms: Receptor-interacting serine/threonine-protein kinase 3, RIPK3,RIP3
Cat. No.: HY-100904R
CAS No.: 89196-95-2
Synonyms: 2 BFI (Standard)
Research Areas:
RX 801077 (hydrochloride) (Standard) is the analytical standard of RX 801077 (hydrochloride) (HY-100904). This product is intended for research and analytical applications. RX 801077 hydrochloride (2 BFI) is a selective imidazoline I2 receptor (I2R) agonist with a Ki value of 70.1 nM. RX 801077 hydrochlorideshows anti-inflammation and neuroprotection. RX 801077 hydrochloride has the potential for the research of traumatic brain injury (TBI) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
