72583-92-7
72583-92-7
Chemical Structure
RX 801077
Synonym(s): 2 BFI free base
- CAS No.: 72583-92-7
- Formula:C11H10N2O
- Molecular Weight:186.21
IUPAC Name: 2-(benzofuran-2-yl)-4,5-dihydro-1H-imidazole
InChIKey: YTJOHEUHUVBKSB-UHFFFAOYSA-N
SMILES: C1(C2=CC3=CC=CC=C3O2)=NCCN1
Biological Activity: RX 801077 (2 BFI free base) is a selective imidazoline I2 receptor (I2R) agonist with a Ki value of 70.1 nM. RX 801077 shows anti-inflammation and neuroprotection. RX 801077 has the potential for the research of traumatic brain injury (TBI)[1][2].
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RX 801077 | RX 801077 (2 BFI free base) is a selective imidazoline I2 receptor (I2R) agonist with a Ki value of 70.1 nM. RX 801077 shows anti-inflammation and neuroprotection. RX 801077 has the potential for the research of traumatic brain injury (TBI). | |||||||||||||||||||||
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References
- [1]. Carpéné C, et al. Inhibition of amine oxidase activity by derivatives that recognize imidazoline I2 sites. J Pharmacol Exp Ther. 1995 Feb;272(2):681-8. [Content Brief]
- [2]. Ni H, et al. 2-BFI Provides Neuroprotection Against Inflammation and Necroptosis in a Rat Model of Traumatic Brain Injury. Front Neurosci. 2019 Jun 26;13:674.
Keywords
