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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
TSPO
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "TSPO" in MCE Product Catalog:
Cat. No.: HY-150410
CAS No.: 2241669-89-4
TSPO ligand-3 is a ligand of AUTAC2. AUTAC2 contains an p-fluorobenzylguanine (FBnG) and an synthetic ligand of FKBP (SLF) moiety, which can cause significant silencing of FKBP12 in HeLa cells .
Cat. No.: HY-172534
Target:
Research Areas:
BPN-01 is a fluorescent probe targeting translocator protein (TSPO) and human epidermal growth factor receptor 2 (HER2) with binding affinities of -10.7 kcal/mol for TSPO and -11.3 kcal/mol for HER2. BPN-01 is promising for research of solid tumor imaging during fluorescence image-guided surgery (FIGS) (Ex/Em = 475/510 nm) .
Cat. No.: HY-19854
CAS No.: 949080-24-4
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TRO-40303 is a cell protective compound targeting mitochondrial TSPO. TRO-40303 significantly improves the survival rate of liver cells and reduces cell death by reducing oxidative stress. TRO-40303 is commonly used in the study of hepatitis .
Cat. No.: HY-15527R
CAS No.: 226954-04-7
Synonyms: AC-5216 (Standard); XBD-173 (Standard)
Target:
Research Areas:
Emapunil (Standard) is the analytical standard of Emapunil. This product is intended for research and analytical applications. Emapunil (AC-5216), an orally active and selective TSPO (a mitochondrial benzodiazepine receptor) ligand, produces anti-anxiety and antidepressant-like effects in various animal models .
Cat. No.: HY-19567R
CAS No.: 85532-75-8
Synonyms: RP 52028 (Standard)
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Research Areas:
PK 11195 (Standard) is the analytical standard of PK 11195. This product is intended for research and analytical applications. PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively.
Cat. No.: HY-122607R
CAS No.: 958233-07-3
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DPA-714 (Standard) is the analytical standard of DPA-714. This product is intended for research and analytical applications. DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. 18FDPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model .
Cat. No.: HY-RS23157
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Tspo Rat Pre-designed siRNA Set A contains three designed siRNAs for Tspo gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-111191R
CAS No.: 895169-20-7
Research Areas:
ONO-2952 (Standard) is the analytical standard of ONO-2952 (HY-111191). This product is intended for research and analytical applications. ONO-2952 is a potent, selective and orally active translocator protein 18 Kda (TSPO) antagonist with Ki of 0.33-9.30 nM for rat and human TSPO. ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels and enzymes. ONO-2952 exerts its anti-stress effects through inhibition of excessive activation of noradrenergic system in the brain without the amnesic effect. ONO-2952 has the potential for irritable bowel syndrome treatment .
Cat. No.: HY-W667746
CAS No.: 386297-97-8
Research Areas:
DPA-713 is a blood-brain barrier-permeable, specific translocator protein (TSPO) ligand. DPA-713 binds exclusively to TSPO without interacting with central benzodiazepine receptors; its binding can be competitively displaced by excess unlabeled TSPO ligands. After 11C labeling, DPA-713 enables sensitive quantitative analysis of TSPO expression associated with microglial activation, allowing differentiation between normal and pathological brain tissues. DPA-713 can be used in studies related to neuroinflammation, neurodegenerative diseases, and recently onset schizophrenia .
Cat. No.: HY-111191AR
CAS No.: 2988224-39-9
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(R)-ONO-2952 (Standard) is the analytical standard of (R)-ONO-2952 (HY-111191A). This product is intended for research and analytical applications. (R)-ONO-2952 is a R-enantiomer of ONO-2952. ONO-2952 is a potent, selective and orally active TSPO antagonist with Kis of 0.33-9.30 nM for rat and human TSPO. ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels and enzymes .
Cat. No.: HY-P702478
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TSPO; Bzrp; Mbr; Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR; PBS; PBRS; PTBR; BPBS; Translocator Protein (18kDa); Benzodiazapine Receptor (Peripheral); Benzodiazepine Peripheral Binding
Species:
Mouse
Source:
E. coli Cell-free
Cat. No.: HY-P706194
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR
Species:
Human
Source:
E. coli Cell-free
Cat. No.: HY-122607S
Cat. No.: HY-186105A
CAS No.: 1597443-57-6
Target:
Research Areas:
(-)-P7C3-S243 is an orally active, blood-brain barrier permeable neuroprotective agent. (-)-P7C3-S243 binds to μ-opioid Receptor and TSPO. (-)-P7C3-S243 inhibits the premature apoptosis death of newborn hippocampal neurons, protects mature nigral dopaminergic neurons, promotes neuronal survival and prevents cognitive impairment. (-)-P7C3-S243 ameliorates depression-like behaviors in rat models. (-)-P7C3-S243 is applicable to research related to Parkinson's disease and Alzheimer's disease .
Cat. No.: HY-P87004
Synonyms: Benzodiazapine receptor (peripheral) antibody; Benzodiazepine peripheral binding site antibody; BPBS antibody; BZRP antibody; DBI antibody; IBP antibody; Isoquinoline carboxamide-binding protein antibody; MBR antibody; mDRC antibody; Mitochondrial benzodiazepine receptor antibody; Benzodiazapine receptor (peripheral) antibody; Benzodiazepine peripheral binding site antibody; BPBS antibody; BZRP antibody; DBI antibody; IBP antibody; Isoquinoline carboxamide-binding protein antibody; MBR antibody; mDRC antibody; Mitochondrial benzodiazepine receptor antibody; PBR antibody; PBS antibody; Peripheral benzodiazepine receptor antibody; Peripheral benzodiazepine receptor-related protein antibody; Peripheral type benzodiazepine receptor antibody; Peripheral-type benzodiazepine receptor antibody; pk18 antibody; PKBS antibody; PTBR antibody; Ptbzr antibody; PTBZR02 antibody; RATPTBZR02 antibody; translocator protein (18kDa) antibody; Translocator protein antibody; TSPO antibody; TSPO1 antibody; TSPOA_HUMAN antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
