85532-75-8
85532-75-8
Chemical Structure
PK 11195
Synonym(s): RP 52028
- CAS No.: 85532-75-8
- Formula:C21H21ClN2O
- Molecular Weight:352.86
IUPAC Name: N-(sec-butyl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide
InChIKey: RAVIZVQZGXBOQO-UHFFFAOYSA-N
SMILES: O=C(N(C(CC)C)C)C1=CC2=CC=CC=C2C(C3=CC=CC=C3Cl)=N1
Biological Activity: PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PK 11195 | 99.91% | PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively. | ||||||||||||||||||||
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PK 11195 (Standard) | ≥98% | PK 11195 (Standard) is the analytical standard of PK 11195. This product is intended for research and analytical applications. PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively. | ||||||||||||||||||||
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PK14105 | 99.59% | PK14105 is identified as a potential PBBS receptor in PET research biological evaluation. | ||||||||||||||||||||
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MS437 | 99.41% | MS437 is a potent TSH receptor (TSHR) stimulator with an EC50 value of 13x10-8 M. MS437 shows potent activation of Gsα, Gαq and Gα12 and up-regulation of thyroglobulin (Tg), sodium iodine symporter (NIS) and TSHR gene expressions. | ||||||||||||||||||||
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AHN 070 | AHN 070 is an irreversible peripheral benzodiazepine receptor (PBR) ligand. AHN 070 can bind to PBR with nanomolar affinity and is pH-dependent. AHN 070 can be used for studying the structure and function of PBR. |
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ER176 | 99.81% | ER176 is a next generation PET radioligand for imaging 18 kDa translocator protein (TSPO), a biomarker for neuroinflammation. | ||||||||||||||||||||
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DRP1 Allosteric-IN-2 | DRP1 Allosteric-IN-2 (Compound 2a) is an allosteric inhibitor of DRP1. Its IC50 value for the DRP1:MiD49 protein-protein interaction is 4.3 μM. DRP1 Allosteric-IN-2 can be used to study various diseases related to mitochondrial division disorders. | |||||||||||||||||||||
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DRP1 Allosteric-IN-3 | DRP1 Allosteric-IN-3 (Compound 2b) is an allosteric inhibitor of DRP1. Its IC50 value for the DRP1:MiD49 protein-protein interaction is 11 μM. DRP1 Allosteric-IN-3 can be used to study various diseases related to mitochondrial division disorders. | |||||||||||||||||||||
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Cinchophen (Standard) | ≥98% | Cinchophen (Standard) is the analytical standard of Cinchophen. This product is intended for research and analytical applications. Cinchophen is a potent and orally active non-steroidal anti-inflammatory agent, has analgesic and antimicrobial effects. Cinchophen can be used for the research of arthritis and some liver diseases. | ||||||||||||||||||||
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Chlorfenazole | 99.85% | Chlorfenazole (o-Chlorobenzimidazole) is a benzimidazole-based compound. Chlorfenazole is used in the research of intestinal nematode diseases. | ||||||||||||||||||||
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6-Chloro-4-(2-chlorophenyl)quinazoline-2-carbaldehyde (Standard) | ≥98% | 6-Chloro-4-(2-chlorophenyl)quinazoline-2-carbaldehyde (Standard) is the analytical standard of 6-Chloro-4-(2-chlorophenyl)quinazoline-2-carbaldehyde. This product is intended for research and analytical applications. | ||||||||||||||||||||
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ent-Calindol amide-13C | ent-Calindol amide-13C is the 13C-labeled ent-Calindol Amide (HY-W740666). | |||||||||||||||||||||
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