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Cat. No.: HY-176974

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DRP1 Allosteric-IN-2

DRP1 Allosteric-IN-2 (Compound 2a) is an allosteric inhibitor of DRP1. Its IC₅₀ value for the DRP1:MiD49 protein-protein interaction is 4.3 μM. DRP1 Allosteric-IN-2 can be used to study various diseases related to mitochondrial division disorders.

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CAS No.: 3056559-91-9
Formule: C₂₁H₂₃N₃O
Masse moléculaire:333.43

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

DRP1 Allosteric-IN-2 Chemical Structure

CAS No.: 3056559-91-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Chemical Information

CAS No. 3056559-91-9
Masse moléculaire 333.43
Formule C₂₁H₂₃N₃O
SMILES

O=C(C(C)C)NC1=CC2=C(N=C(C3=CC=CC=C3)C=C2NCC)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Staben LR, et al. Systematic Variation of Pyrrolobenzodiazepine (PBD)-Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody-Drug Conjugates. J Med Chem. 2020 Sep 10;63(17):9603-9622. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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