226954-04-7
226954-04-7
Chemical Structure
Emapunil
Synonym(s): AC-5216; XBD-173
- CAS No.: 226954-04-7
- Formula:C23H23N5O2
- Molecular Weight:401.46
IUPAC Name: N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide
InChIKey: NBMBIEOUVBHEBM-UHFFFAOYSA-N
SMILES: O=C(N(CC)CC1=CC=CC=C1)CN2C(N(C)C3=CN=C(C4=CC=CC=C4)N=C23)=O
Biological Activity: Emapunil (AC-5216), an orally active and selective TSPO (a mitochondrial benzodiazepine receptor) ligand, produces anti-anxiety and antidepressant-like effects in various animal models[1][2].
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Emapunil | 99.94% | Emapunil (AC-5216), an orally active and selective TSPO (a mitochondrial benzodiazepine receptor) ligand, produces anti-anxiety and antidepressant-like effects in various animal models. | ||||||||||||||||||||
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Emapunil (Standard) | ≥98% | Emapunil (Standard) is the analytical standard of Emapunil. This product is intended for research and analytical applications. Emapunil (AC-5216), an orally active and selective TSPO (a mitochondrial benzodiazepine receptor) ligand, produces anti-anxiety and antidepressant-like effects in various animal models. | ||||||||||||||||||||
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References
- [1]. Atsuko Kita, et al. Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligand. Br J Pharmacol. 2004 Aug;142(7):1059-72. [Content Brief]
- [2]. Marcus Karlstetter, et al. Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis. J Neuroinflammation. 2014 Jan 8;11:3. [Content Brief]
Keywords
