Nampt-IN-21
Nampt-IN-21 is a NAMPT inhibitor. Nampt-IN-21 serves as a Ligand for Target Protein for PROTAC for the synthesis of PROTAC NAMPT degraders, such as PROTAC NAMPT Degrader-30 (HY-152154). Nampt-IN-21 is applicable to the research of ovarian cancer.
For research use only. We do not sell to patients.
- CAS No.: 1110983-52-2
- Formula: C24H22N4O2
- Molecular Weight:398.46
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
99 nM
Compound: M0490244; A1
|
Cytotoxicity against human A2780 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
Cytotoxicity against human A2780 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay
|
[PMID: 36442664] |
| HepG2 | IC50 |
1.95 μM
Compound: 37; M049-0244
|
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay
|
[PMID: 38244254] |
Chemical Information
-
CAS No. 1110983-52-2
-
Molecular Weight 398.46
-
Formula C24H22N4O2
-
SMILES
O=C(C(C1=CC=C(C=C1)C(NCC2=CN=CC=C2)=O)=NC3=C4C=CC=C3)N4CCC
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nampt-IN-21 Related Classifications
HY-187006 Related Classifications
Powered by Bioz